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TGIF Antibody (K-15): sc-9825

 |  Datasheet

(Based on data analysis)

  • TGIF Antibody (K-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of TGIF of human origin
  • recommended for detection of TGIF of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and bovine
  • blocking peptide, sc-9825 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-9825 X, 200 µg/0.1 ml
  • See 1 citations for TGIF Antibody (K-15)
 

See additional TGIF Antibodies including TGIF, TGIF2, TGIF2LX, TGIF2LY and TGIF2LX1.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
TGIF Antibody (K-15) sc-9825 200 µg/ml $279
TGIF (K-15) P sc-9825 P
(peptide)
 100 µg/0.5 ml $61
TGIF Antibody (K-15) X sc-9825 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TGIF siRNA (h) sc-36659 10 µM $258
TGIF siRNA (m) sc-36660 10 µM $258
TGIF (h)-PR sc-36659-PR 10 µM, 20 µl $23
TGIF (m)-PR sc-36660-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TGIF shRNA Plasmid (h) sc-36659-SH 20 µg $520
TGIF shRNA Plasmid (m) sc-36660-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TGIF shRNA (h) Lentiviral Particles sc-36659-V 200 µl $625
TGIF shRNA (m) Lentiviral Particles sc-36660-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
JAR Cell Lysate sc-2276 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
TGIF (h): 293 Lysate sc-110546 100 µg/200 µl $205
SW480 nuclear extract sc-2155 250 µg/0.05 ml $143
TGIF (m): 293T Lysate sc-124025 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TGIF1 7050 18p11.31 NM_003244, NM_170695, NM_173207, NM_173208, NM_173209, NM_173210, NM_173211, NM_174886 Q15583
 n/a
Mouse Tgif1 21815 17 E1.3 P70284
 N/A
 

TGIF (5’-TG-3’ interacting factor) was originally identified as a homeo-domain protein that binds to a retinoid X receptor (RXR) responsive element, thereby inhibiting the binding of RXR to this site and repressing RXR-dependent transcriptional activation. TGIF is a member of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. TGIF also binds to Smad2, to repress Smad2-Smad4-mediated transcription. Smad2, after phosphorylation mediated by TGF∫ receptor, forms a complex with Smad4 and enters the nucleus to regulate transcription. The Smad2-Smad4 complex can interact with coactivators to form a transcriptional activation complex. Alternatively, the Smad2-Smad4 complex can interact with TGIF and HDACs to form a transcriptional repressor complex. Upon interaction with Smad2, TGIF is recruited to TGF∫-responsive genes, where it acts to repress TGF∫-induced transcription.

TGIF Antibody (K-15) Product Citations
See how others have used TGIF Antibody (K-15) and or TGIF Antibody (K-15) conjugates.


1 total citations
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TGIF Antibody (K-15) Data
Click on image to enlarge
sc-9825
TGIF (K-15): sc-9825. Western blot analysis of TGIF expression in rat placenta tissue extract.
sc-9825
TGIF (K-15): sc-9825. Western blot analysis of TGIF expression in non-transfected: sc-110760 (A) and human TGIF transfected: sc-110546 (B) 293 whole cell lysates.
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