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Six1 Antibody (A-20): sc-9709

 |  Datasheet

(Based on data analysis)

  • Six1 Antibody (A-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of Six1 of human origin
  • recommended for detection of Six1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine and porcine
  • blocking peptide, sc-9709 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-9709 X, 200 µg/0.1 ml
  • See 3 citations for Six1 Antibody (A-20)
 

See additional Six Antibodies including Six, Six1, Six2, Six3, Six4, Six5 and Six6.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Six1 Antibody (A-20) sc-9709 200 µg/ml $279
Six1 (A-20) P sc-9709 P
(peptide)
 100 µg/0.5 ml $61
Six1 Antibody (A-20) X sc-9709 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Six1 siRNA (h) sc-38784 10 µM $258
Six1 siRNA (m) sc-38785 10 µM $258
Six1 (h)-PR sc-38784-PR 10 µM, 20 µl $23
Six1 (m)-PR sc-38785-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Six1 shRNA Plasmid (h) sc-38784-SH 20 µg $520
Six1 shRNA Plasmid (m) sc-38785-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Six1 shRNA (h) Lentiviral Particles sc-38784-V 200 µl $625
Six1 shRNA (m) Lentiviral Particles sc-38785-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Six1 (m): 293T Lysate sc-123562 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SIX1 6495 14q23.1 NM_005982 Q15475
 608389
Mouse Six1 20471 12 C3 Q62231
 N/A
 

The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. SIX2, SIX4 (AREC3) and SIX5 bind to the same DNA sequence, indicating that they may regulate the same target genes. SIX1 and SIX4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint.

Six1 Antibody (A-20) Product Citations
See how others have used Six1 Antibody (A-20) and or Six1 Antibody (A-20) conjugates.


3 total citations
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Six1 Antibody (A-20) Data
Click on image to enlarge
sc-9709
Six1 (A-20): sc-9709. Western blot analysis of Six1 expression in non-transfected: sc-117752 (A) and mouse Six1 transfected: sc-123562 (B) 293T whole cell lysates.
sc-9709
Six1 (A-20): sc-9709. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear staining of respiratory epithelial cells.
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