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MEK-3 Antibody (N-20): sc-959

 |  Datasheet

(Based on data analysis)

  • MEK-3 Antibody (N-20) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of MEK-3 of human origin
  • recommended for detection of MEK-3 and, to a lesser extent, MEK-6 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
  • blocking peptide, sc-959 P
  • See 14 citations for MEK-3 Antibody (N-20)
 

See additional MEK Antibodies including MEK, MEK, MEK-1, MEK-2, MEK-3, MEK-4, MEK-5, MEK-6 and MEK-7.

Also see MEK Inhibitors or MEK Activators for functional analysis of cellular responses to MEK.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
MEK-3 Antibody (N-20) sc-959 200 µg/ml $279
MEK-3 (N-20) P sc-959 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MEK-3/6 siRNA (h) sc-43924 10 µM $258
MEK-3/6 (h)-PR sc-43924-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MEK-3/6 shRNA Plasmid (h) sc-43924-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MEK-3/6 shRNA (h) Lentiviral Particles sc-43924-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
WEHI-231 Whole Cell Lysate sc-2213 500 µg/200 µl $104
CTLL-2 Cell Lysate sc-2242 500 µg/200 µl $104
MEK-3 (h): 293T Lysate sc-114954 100 µg/200 µl $205
MEK-3 (h2): 293T Lysate sc-176353 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MAP2K3 5606 17p11.2 NM_002756, NM_145109, NM_145110 P46734
 602315
Mouse Map2k3 26397 11 B2 O09110
 N/A
 

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

MEK-3 Antibody (N-20) Product Citations
See how others have used MEK-3 Antibody (N-20) and or MEK-3 Antibody (N-20) conjugates.


14 total citations
Loading citations.
 
MEK-3 Antibody (N-20) Data
Click on image to enlarge
sc-959
MEK-3 (N-20): sc-959. Western blot analysis of MEK-3 expression in HeLa (A), Jurkat (B), NIH/3T3 (C), WEHI-231 (D) and CTLL-2 (E) whole cell lysates.
sc-959
MEK-3 (N-20): sc-959. Western blot analysis of MEK-3 expression in non-transfected: sc-117752 (A) and human MEK-3 transfected: sc-114954 (B) 293T whole cell lysates.
sc-959
MEK-3 (N-20): sc-959. Western blot analysis of MEK-3 expression in 293T (A) and HeLa (B) whole cell lysates.
sc-959
MEK-3 (N-20): sc-959. Western blot analysis of MEK-3 expression in non-transfected: sc-117752 (A) and human MEK-3 transfected: sc-176353 (B) 293T whole cell lysates.
sc-959
MEK-3 (N-20): sc-959. Immunofluorescence staining of methanol-fixed untransfected (A) and human MEK-3 transfected HEK 293T cells (B).
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