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PA26 Antibody (I-20): sc-9505

 |  Datasheet

(Based on data analysis)

  • PA26 Antibody (I-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of PA26 of human origin
  • recommended for detection of all PA26 isoforms of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-9505 P
 

See additional PA26 Antibodies including PA26, PA26-T1, PA26-T2 and PA26-T3.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
PA26 Antibody (I-20) sc-9505 200 µg/ml $279
PA26 (I-20) P sc-9505 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PA26 siRNA (h) sc-37420 10 µM $258
PA26 siRNA (m) sc-37421 10 µM $258
PA26 (h)-PR sc-37420-PR 10 µM, 20 µl $23
PA26 (m)-PR sc-37421-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PA26 shRNA Plasmid (h) sc-37420-SH 20 µg $520
PA26 shRNA Plasmid (m) sc-37421-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PA26 shRNA (h) Lentiviral Particles sc-37420-V 200 µl $625
PA26 shRNA (m) Lentiviral Particles sc-37421-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SESN1 27244 6q21 NM_014454 Q9Y6P5
 606103
Human SESN2 83667 1p35.3 NM_031459 P58004
 607767
Human SESN3 143686 11q21 NM_144665 P58005
 607768
Mouse Sesn1 140742 10 B2 P58006
 N/A
 

Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
PA26 Antibody (I-20) Data
Click on image to enlarge
sc-9505
PA26 (I-20): sc-9505. Western blot analysis of PA26 expression in non-transfected: sc-117752 (A) and mouse PA26 transfected: sc-122341 (B) 293T whole cell lysates.
sc-9505
PA26 Antibody (I-20): sc-9505. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic and nuclear staining of glandular cells.
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