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Rac 1 (C-11) Antibody: sc-95

 |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope mapping within the C-terminus of Rac 1 of human origin
  • recommended for detection of Rac 1 and, to a lesser extent, Rac 3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; non cross-reactive with Rac 2; also reactive with additional species, including canine
  • blocking peptide, sc-95 P
 
Additional Rac Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RAC1 5879 7p22.1 NM_006908, NM_018890, NM_198829 P63000
602048
Mouse Rac1 19353 5 G2 P63001
N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Rac 1 (C-11) sc-95 200 µg/ml $279
Rac 1 (C-11) P sc-95 P
(peptide)
100 µg/0.5 ml $61
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
Rac 1 (m): 293T Lysate sc-122932 100µg/200µl $205
Rac 1 (h): 293T Lysate sc-116394 100µg/200µl $205
Rac 1 (m2): 293T Lysate sc-122933 100µg/200µl $205

Rac 1 Background Information
A large number of low molecular weight, GTP binding proteins of the Ras superfamily have been identified. These proteins regulate many fundamental processes in all eukaryotic cells such as growth, vesicle traffic and cytoskeletal organization. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. Two proteins in this family, Rac 1 and Rac 2, are 92% identical and share GTP binding and GTP hydrolysis motifs with other members of the Ras superfamily. Rac 1 is expressed in a large number of different cell types. Rac 2 is primarily expressed only in myeloid cells and has been reported to be a regulatory component of the human neutrophil NADPH oxidase.

Rac 1 (C-11) Product Citations
See how others have used Rac 1 (C-11): sc-95 antibody and or Rac 1 (C-11) antibody conjugates.


22 total citations
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Rac 1 (C-11)
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Rac 1 (C-11): sc-95. Western blot analysis of human recombinant Rac 1 fusion protein.
Rac 1 (C-11): sc-95. Western blot analysis of Rac 1 expression in non-transfected: sc-117752 (A) and mouse Rac 1 transfected: sc-122933 (B) 293T whole cell lysates.
Rac 1 (C-11): sc-95. Western blot analysis of Rac 1 expression in non-transfected: sc-117752 (A) and human Rac 1 transfected: sc-116394 (B) 293T whole cell lysates.
Rac 1 (C-11): sc-95. Western blot analysis of Rac 1 expression in non-transfected 293T: sc-117752 (A), mouse Rac 1 transfected 293T: sc-122932 (B) and A-431 (C) whole cell lysates.
Rac 1 (C-11): sc-95. Western blot analysis of Rac 1 expression in A-431 whole cell lysate.
Rac 1 (C-11): sc-95. Western blot analysis of Rac 1 expression in HL-60 whole cell lysate.
Rac 1 (C-11): sc-95. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing cytoplasmic staining of glandular cells.
Western blot analysis of Rac 1 phosphorylation in untreated (A,C) and lambda protein phosphatase (sc-200312A) treated (B,D) HL-60 whole cell lysates. Antibodies tested include p-Rac 1 (Ser 71)-R: sc-12924-R (A,B) and Rac 1 (C-11): sc-95 (C,D).
Western blot analysis of Rac 1 phosphorylation in untreated (A,C) and lambda protein phosphatase (sc-200312A) treated (B,D) 293T whole cell lysates. Antibodies tested include p-Rac 1 (Ser 71)-R: sc-12924-R (A,B) and Rac 1 (C-11): sc-95 (C,D).
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