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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the N-terminus of FOG of mouse origin
- recommended for detection of FOG of mouse, rat and human origin by WB, IP, IF and ELISA
- blocking peptide, sc-9361 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-9361 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
ZFPM1 |
161882 |
16q24.2 |
NM_153813 |
Q8IX07
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601950 |
| Mouse |
Zfpm1 |
22761 |
8 E1 |
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O35615
|
N/A |
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FOG Background Information
The FOG family of transcriptional cofactors, including FOG (friend of GATA-1) and FOG-2, are zinc finger proteins that interact with the GATA family of transcriptional regulators. FOG/GATA-1 complexes are required for erythroid and megakaryocyte maturation, and they promote differentiation during embryonic development. These complexes involve the association between multiple zinc fingers on the FOG proteins and the N-terminal zinc finger of GATA proteins. While FOG cooperatively regulates GATA-1 induced transcription, FOG-2 is able to both positively and negatively influence GATA mediated transcription. FOG-2 is predominantly expressed in heart, neurons and gonads, and it preferentially participates in the regulation of GATA-3, GATA-4 and GATA-6. In cardiomyocytes and fibroblasts, FOG-2 inhibits GATA-4 transcriptional activity, yet FOG-2 restores GATA-1 mediated transcription in erythroid cultures deficient in FOG, suggesting that the observed effects of FOG-2 are context specific and vary between cellular systems.
| FOG (M-20) Product Citations |
See how others have used FOG (M-20): sc-9361 antibody and or FOG (M-20) antibody conjugates.
16 total citations Loading citations.
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FOG (M-20)
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FOG (M-20): sc-9361. Western blot analysis of FOG expression in rat testis extract.
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