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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of Ang-4 of human origin
- recommended for detection of Ang-1 of mouse, rat and human origin and Ang-4 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA
- blocking peptide, sc-9360 P
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
ANGPT4 |
51378 |
20p13 |
NM_015985 |
Q9Y264
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603705 |
| Mouse |
Angpt1 |
11600 |
15 B3.1 |
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O08538
|
N/A |
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Ang-1/4 Background Information
Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. Ang-1 is glycosylated and has a fibrinogen-like domain at the carboxy terminus and coiled-coil regions in the amino terminus. Ang-1 is an angiogenic factor that mediates blood vessel maturation and may be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), is a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression is restricted to sites of vascular remodeling. Ang-1 and Ang-2 are expressed in human malignant glioma. Ang-3 is a secretory protein expressed in adult human adrenal gland, placenta, lung, cultured human umbilical vein endothelial cells, thyroid gland, heart and small intestine. It acts as an antagonist. Ang-4 is expressed in heart and acts as an agonist.
| Ang-1/4 (C-19) Product Citations |
See how others have used Ang-1/4 (C-19): sc-9360 antibody and or Ang-1/4 (C-19) antibody conjugates.
8 total citations Loading citations.
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Ang-1/4 (C-19)
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Ang-1/4 (C-19): sc-9360. Western blot analysis of Ang-1/4 expression in ECV304 (A), HEL 92.1.7 (B), HeLa (C), HeLa + TNFα (D) and LADMAC (E) whole cell lysates.
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