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AKAP 13 Antibody (R-19): sc-9336

 |  Datasheet

(Based on data analysis)

  • AKAP 13 Antibody (R-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of AKAP 13 of human origin
  • recommended for detection of Brx of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and bovine
  • blocking peptide, sc-9336 P
 

See additional AKAP Antibodies including AKAP 14, AKAP, AKAP 13, AKAP 149/121, AKAP 3, AKAP 7, AKAP 8L, AKAP 9, AKAP 10, AKAP 12, AKAP 79, AKAP 82, AKAP 95, AKAP 100, AKAP 121, AKAP 149, AKAP 150, AKAP 220, AKAP 2 and AKAP 250.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
AKAP 13 Antibody (R-19) sc-9336 200 µg/ml $279
AKAP 13 (R-19) P sc-9336 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AKAP 13 siRNA (h) sc-41721 10 µM $258
AKAP 13 siRNA (m) sc-41722 10 µM $258
AKAP 13 (h)-PR sc-41721-PR 10 µM, 20 µl $23
AKAP 13 (m)-PR sc-41722-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AKAP 13 shRNA Plasmid (h) sc-41721-SH 20 µg $520
AKAP 13 shRNA Plasmid (m) sc-41722-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AKAP 13 shRNA (h) Lentiviral Particles sc-41721-V 200 µl $625
AKAP 13 shRNA (m) Lentiviral Particles sc-41722-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human AKAP13 11214 15q25.3 NM_006738, NM_007200, NM_144767 Q12802
 604686
 

The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. The family of RII-anchoring proteins has been designated A-kinase anchoring proteins (AKAP). AKAP 13, also known as BRX (breast cancer nuclear receptor-binding auxiliary protein), LBC (lymphoid blast crisis oncogene), HA-3 or Ht31 (human thyroid-anchoring protein 31), functions as a cAMP-dependent scaffold anchor for PKA and also has Rho-GEF activity. It is known to regulate TLR2 signaling, NF˚B activation, protein kinase D activation and participate in actin stress fiber formation. Seven isoforms exist for AKAP 13 and, depending on the isoform, it localizes to the cytoplasm, nucleus or cell membrane.
AKAP 13 Antibody (R-19) Data
Click on image to enlarge
sc-9336
AKAP 13 (R-19): sc-9336. Western blot analysis of AKAP 13 expression in human heart tissue extract.
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