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ANT (N-19) Antibody: sc-9299

 |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the N-terminus of ANT of human origin
  • recommended for detection of all ANT isoforms of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including bovine, porcine and avian
  • blocking peptide, sc-9299 P
  • phycoerythrin (sc-9299 PE) conjugate for intracellular FCM, 100 tests
 
Additional ANT Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   FCM   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SLC25A4 291 4q35.1 NM_001151 P12235
609283
Human SLC25A5 292 Xq24 NM_001152 P05141
300150
Mouse Slc25a4 11739 8 B1.1 P48962
N/A
Mouse Slc25a5 11740 X A3.3 P51881
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
ANT (N-19) sc-9299 200 µg/ml $279
ANT (N-19) P sc-9299 P
(peptide)
100 µg/0.5 ml $61
ANT (N-19) PE sc-9299 PE 100 tests in 2ml $303
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ANT siRNA (h) sc-42353 10 µM $258
ANT siRNA (m) sc-42354 10 µM $258
ANT (h)-PR sc-42353-PR 10 µM $23
ANT (m)-PR sc-42354-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ANT shRNA Plasmid (h) sc-42353-SH 20 µg $520
ANT shRNA Plasmid (m) sc-42354-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ANT shRNA (h) Lentiviral Particles sc-42353-V 200 µl $625
ANT shRNA (m) Lentiviral Particles sc-42354-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
mouse heart extract sc-2254 500 µg/200 µl $104
ANT (m): 293T Lysate sc-118438 100µg/200µl $205

ANT Background Information
Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.

ANT (N-19) Product Citations
See how others have used ANT (N-19): sc-9299 antibody and or ANT (N-19) antibody conjugates.


17 total citations
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ANT (N-19)
Click on image to enlarge
ANT (N-19): sc-9299. Western blot analysis of ANT expression in mouse heart (A) and rat skeletal muscle (B) tissue extracts.
ANT (N-19) PE: sc-9299 PE. Intracellular FCM analysis of fixed and permeabilized L8 cells. Black line histogram represents the isotype control, normal goat IgG: sc-3992.
ANT (N-19): sc-9299. Immunofluorescence staining of methanol-fixed Sol8 cells showing cytoplasmic localization.
ANT (N-19): sc-9299. Western blot analysis of ANT expression in mouse heart tissue extract.
ANT (N-19): sc-9299. Western blot analysis of ANT expression in mouse heart tissue extract.
ANT (N-19): sc-9299. Western blot analysis of ANT expression in rat skeletal muscle tissue extract.
ANT (N-19): sc-9299. Western blot analysis of ANT expression in non-transfected: sc-117752 (A) and mouse ANT transfected: sc-118438 (B) 293T whole cell lysates.
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