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Insulin Antibody (H-86): sc-9168

 |  Datasheet

(Based on data analysis)

  • Insulin Antibody (H-86) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 25-110 of Insulin of human origin
  • recommended for detection of Insulin A and B chains, and C peptide of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine and canine
  • See 46 citations for Insulin Antibody (H-86)
 
Full-length Insulin protein sequence with immunogen highlighted:
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN

See additional Insulin Antibodies including Insulin, Insulin A and Insulin B.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Insulin Antibody (H-86) sc-9168 200 µg/ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Insulin CRISPR/Cas9 KO Plasmid (h) sc-400149 20 µg $345
Insulin HDR Plasmid (h) sc-400149-HDR 20 µg $385
Insulin I CRISPR/Cas9 KO Plasmid (m) sc-421139 20 µg $345
Insulin I HDR Plasmid (m) sc-421139-HDR 20 µg $385
Insulin II CRISPR/Cas9 KO Plasmid (m) sc-421140 20 µg $345
Insulin II HDR Plasmid (m) sc-421140-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Insulin siRNA (h) sc-39578 10 µM $258
Insulin (h)-PR sc-39578-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Insulin shRNA Plasmid (h) sc-39578-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Insulin shRNA (h) Lentiviral Particles sc-39578-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MIA PaCa-2 Cell Lysate sc-2285 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human INS 3630 11p15.5 NM_000207 P01308
176730
Mouse Ins1 16333 19 D2 P01325
N/A
Mouse Ins2 16334 7 F5 P01326
N/A
 


Insulin is a secreted peptide hormone that elicits metabolic effects such as increases in glucose uptake and glycogen synthesis leading to a decrease in blood glucose concentration. Insulin is first formed as a precursor molecule, preproinsulin, which is later cleaved to proinsulin and finally to the mature insulin hormone. Mature insulin consists of 51 amino acids, contained within an A chain and a B chain that are connected by two disulfide bridges. It increases cell permeability to monosaccharides, amino acids and fatty acids. Insulin is secreted by the pancreas at basal levels in the absence of exogenous stimuli, with secretion increasing in response to glucose. Insulin action is effected by the binding of insulin to cell-surface receptors on the target cell membrane. Defects of insulin are the cause of hyperproinsulinemia and of type-II diabetes mellitus.

Insulin Antibody (H-86) Product Citations
See how others have used Insulin Antibody (H-86) and or Insulin Antibody (H-86) conjugates.


46 total citations
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