Thy-1 Background Information Over 100 cell surface markers have been identified through the use of monoclonal antibodies. Many of these markers have proven useful in identifying specific subpopulations of cells within mixed colonies. Accordingly, these molecules have been assigned a “cluster of differentiation” (CD) designation. One such marker, designated Thy-1 (also referred to as CDw90), is a phosphatidyl-anchored cell surface glycoprotein which, when coexpressed with CD34 on cells from normal human bone marrow, identifies a subpopulation that includes putative hematopoietic, pleuripotent stem cells. Thy-1+ cells from bone marrow have been implicated in syngeneic graft versus host disease and may serve to regulate autoreactivity after bone marrow transplant.
Thy-1 (H-110) Product Citations
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Thy-1 (H-110)
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Thy-1 (H-110): sc-9163. Western blot analysis of Thy-1 expression in SUP-T1 whole cell lysate.
Thy-1 (H-110): sc-9163. Western blot analysis of Thy-1 expression in IMR-32 (A), CCRF-CEM (B) and MOLT-4 (C) whole cell lysates and rat brain tissue extract (D).
Thy-1 (H-110): sc-9163. Western blot analysis of Thy-1 expression in non-transfected: sc-117752 (A) and human Thy-1 transfected: sc-117078 (B) 293T whole cell lysates.
Thy-1 (H-110): sc-9163. Western blot analysis of Thy-1 expression in non-transfected 293T: sc-117752 (A), human Thy-1 transfected 293T: sc-159201 (B) and mouse PBL (C) whole cell lysates.