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home » Transcription Regulators » UBF Antibody / UBF Antibodies » UBF (H-300): sc-9131

UBF (H-300) Antibody: sc-9131

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-220 representing the N-terminus of UBF of human origin
  • recommended for detection of UBF1 and UBF2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-9131 X, 200 µg/0.1 ml
 
Additional UBF Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human UBTF 7343 17q21.31 NM_014233 P17480
 600673
Mouse Ubtf 21429 11 D P25976
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
UBF (H-300) sc-9131 200 µg/ml $279
UBF (H-300) X sc-9131 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
UBF siRNA (h) sc-29514 10 µM $258
UBF siRNA (m) sc-29515 10 µM $258
UBF1 (h)-PR sc-29514-PR 10 µM $23
UBF1 (m)-PR sc-29515-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
UBF1 shRNA Plasmid (h) sc-29514-SH 20 µg $520
UBF1 shRNA Plasmid (m) sc-29515-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
UBF1 shRNA (h) Lentiviral Particles sc-29514-V 200 µl $625
UBF1 shRNA (m) Lentiviral Particles sc-29515-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A-431 nuclear extract sc-2122 1000 µg $143
KNRK nuclear extract sc-2141 1000 µg $143
HeLa nuclear extract sc-2120 1000 µg $143

UBF Background Information
The transcription of ribosomal RNA genes by RNA polymerase I (Pol I) is tightly coordinated with the growth state of the cell. In addition to Pol I, transcription of ribosomal genes requires the trans-activating factor UBF (upstream binding factor). UBF functions by binding to DNA elements within the RNA gene promoter and enhancer regions and directly associating with Pol I, tethering it to the promoter complex. Two UBF proteins arise from the same gene as a result of alternative mRNA splicings. UBF activity is regulated by several dependent casein kinase II phosphorylates at the carboxy terminus of UBF on serine residues. The retinoblastoma susceptibility gene product, Rb, when not bound to E2F family members, inhibits UBF activity. Expression of RNA may also be negatively regulated by the two Ku antigens.

UBF (H-300) Product Citations
See how others have used UBF (H-300): sc-9131 antibody and or UBF (H-300) antibody conjugates.


12 total citations
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UBF (H-300)
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sc-9131
UBF (H-300): sc-9131. Western blot analysis of UBF expression in A-431 nuclear extract.
sc-9131
UBF (H-300): sc-9131. Western blot analysis of UBF expression in SW480 (A), KNRK (B), PC-3 (C), Hep G2 (D) and TH-1 (E) nuclear extracts.
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