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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of MMP-7 of human origin
- recommended for detection of MMP-7 of mouse, rat and human origin by WB, IP, IF and ELISA
- blocking peptide, sc-8832 P
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
MMP7 |
4316 |
11q22.2 |
NM_002423 |
P09237
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178990 |
| Mouse |
Mmp7 |
17393 |
9 A1 |
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Q10738
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N/A |
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MMP-7 Background Information
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan (1). Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) (2). MMP catalysis requires both calcium and zinc (3). MMP-7 (also designated Pump-1, matrilysin or uterine metalloproteinase) degrades casein, fibronectin and gelatin types I, III, IV and V (4,5). MMP-7 mRNA is produced exclusively by epithelial cells in mouse and expression is restricted to specific organs, suggesting that in addition to matrix degradation and remodeling, MMP-7 may be involved in the differentiated function of these organs (6).
| MMP-7 (C-17) Product Citations |
See how others have used MMP-7 (C-17): sc-8832 antibody and or MMP-7 (C-17) antibody conjugates.
5 total citations Loading citations.
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MMP-7 (C-17)
Click on image to enlarge
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MMP-7 (C-17): sc-8832. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
MMP-7 (C-17): sc-8832. Western blot analysis of MMP-7 expression in non-transfected: sc-117752 (A) and human MMP-7 transfected: sc-158741 (B) 293T whole cell lysates. |
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