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home » Transcription Regulators » FEN Antibody / FEN Antibodies » FEN-1 (C-16): sc-8795

FEN-1 (C-16) Antibody: sc-8795

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the C-terminus of FEN-1 of human origin
  • recommended for detection of FEN-1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-8795 P
 
Additional FEN Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human FEN1 2237 11q12.2 NM_004111 P39748
 600393
Mouse Fen1 14156 19 A P39749
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
FEN-1 (C-16) sc-8795 200 µg/ml $279
FEN-1 (C-16) P sc-8795 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
FEN-1 siRNA (h) sc-37795 10 µM $258
FEN-1 siRNA (m) sc-37796 10 µM $258
FEN-1 (h)-PR sc-37795-PR 10 µM $23
FEN-1 (m)-PR sc-37796-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
FEN-1 shRNA Plasmid (h) sc-37795-SH 20 µg $520
FEN-1 shRNA Plasmid (m) sc-37796-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
FEN-1 shRNA (h) Lentiviral Particles sc-37795-V 200 µl $625
FEN-1 shRNA (m) Lentiviral Particles sc-37796-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa nuclear extract sc-2120 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143
NIH/3T3 nuclear extract sc-2138 1000 µg $143
Y79 Cell Lysate sc-2240 500 µg/200 µl $104
PC-12 Cell Lysate sc-2250 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Y79 nuclear extract sc-2126 1000 µg $143
MCF7 nuclear extract sc-2149 1000 µg $143

FEN-1 Background Information
DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. FEN-1 (for flap endonuclease) is an endonuclease that specifically cleaves the 5’ flap structure of DNA in the process of DNA repair. FEN-1 is highly homologous to yeast RAD2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication.
FEN-1 (C-16)
Click on image to enlarge
sc-8795
FEN-1 (C-16): sc-8795. Western blot analysis of FEN-1 expression in HeLa (A), Jurkat (B) and NIH/3T3 (C) nuclear extracts and Y79 (D) and PC-12 (E) whole cell lysates.
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