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DEPTOR Antibody (N-14): sc-87692

 |  Datasheet

(Based on data analysis)

  • DEPTOR Antibody (N-14) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of DEPTOR of human origin
  • recommended for detection of DEPDC6 of mouse, rat and human origin by WB, IP, IF and ELISA
  • blocking peptide, sc-87692 P
 

See additional DEPTOR Antibodies.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
DEPTOR Antibody (N-14) sc-87692 200 µg/ml $279
DEPTOR (N-14) P sc-87692 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DEPTOR siRNA (h) sc-77660 10 µM $258
DEPTOR siRNA (m) sc-143009 10 µM $258
DEPTOR (h)-PR sc-77660-PR 10 µM, 20 µl $23
DEPTOR (m)-PR sc-143009-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DEPTOR shRNA Plasmid (h) sc-77660-SH 20 µg $520
DEPTOR shRNA Plasmid (m) sc-143009-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DEPTOR shRNA (h) Lentiviral Particles sc-77660-V 200 µl $625
DEPTOR shRNA (m) Lentiviral Particles sc-143009-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DEPDC6 64798 8q24.12 Q8TB45
n/a
 


DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

DEPTOR Antibody (N-14) Data
Click on image to enlarge
DEPTOR (N-14): sc-87692. Western blot analysis of DEPTOR expression in non-transfected: sc-117752 (A) and human DEPTOR transfected: sc-128441 (B) 293T whole cell lysates.
DEPTOR (N-14): sc-87692. Western blot analysis of DEPTOR expression in non-transfected: sc-117752 (A) and human DEPTOR transfected: sc-111088 (B) 293T whole cell lysates.
DEPTOR (N-14): sc-87692. Western blot analysis of DEPTOR expression in mouse testis tissue extract (A) and HeLa whole cell lysate (B).
DEPTOR (N-14): sc-87692. Western blot analysis of DEPTOR expression in non-transfected 293T: sc-117752 (A), mouse DEPTOR transfected 293T: sc-178518 (B), Ramos (C) and U266 (D) whole cell lysates.
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