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home » Signaling Intermediates » TRAF Antibody / TRAF Antibodies » TRAF2 (C-20): sc-876

TRAF2 (C-20) Antibody: sc-876

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of TRAF2 of human origin
  • recommended for detection of TRAF2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-876 P
  • agarose conjugate for IP studies, sc-876 AC, 500 µg/0.25 ml agarose
 
Additional TRAF Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TRAF2 7186 9q34.3 NM_021138 Q12933
 601895
Mouse Traf2 22030 2 A3 P39429
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
TRAF2 (C-20) sc-876 200 µg/ml $279
TRAF2 (C-20) AC sc-876 AC 500µg/ml, 25%ag $366
TRAF2 (C-20) P sc-876 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TRAF2 siRNA (h) sc-29509 10 µM $258
TRAF2 siRNA (m) sc-36711 10 µM $258
TRAF2 siRNA (h2) sc-44276 10 µM $258
TRAF2 (h)-PR sc-29509-PR 10 µM $23
TRAF2 (m)-PR sc-36711-PR 10 µM $23
TRAF2 (h2)-PR sc-44276-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TRAF2 shRNA Plasmid (h) sc-29509-SH 20 µg $520
TRAF2 shRNA Plasmid (m) sc-36711-SH 20 µg $520
TRAF2 shRNA Plasmid (h2) sc-44276-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TRAF2 shRNA (h) Lentiviral Particles sc-29509-V 200 µl $625
TRAF2 shRNA (m) Lentiviral Particles sc-36711-V 200 µl $625
TRAF2 shRNA (h2) Lentiviral Particles sc-44276-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
TRAF2 (h7): 293T Lysate sc-178076 100µg/200µl $205
TRAF2 (h8): 293T Lysate sc-178077 100µg/200µl $205
TRAF2 (m): 293T Lysate sc-127697 100µg/200µl $205
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
TRAF2 (h8): 293T Lysate sc-178077 100µg/200µl $205
TRAF2 (h10): 293T Lysate sc-178079 100µg/200µl $205

TRAF2 Background Information
Tumor necrosis factor (TNF)-activated cell signaling is mediated primarily through the TNF receptor 1 (TNF-R1) and, to a lesser extent, TNF-R2. Both TNF receptors are members of the expanding TNF receptor superfamily, which includes the FAS antigen and CD40. Potential insight into an understanding of TNF receptor-mediated signaling was provided by the identification of two related proteins, TRAF1 and TRAF2 (for TNF receptor-associated factors 1 and 2, respectively). Both function to form heterodimeric complexes and associate with the cytoplasmic domain of TNF-R2. A third member of this protein family, alternatively designated CD40 bp, CRAF1, LAP1 or TRAF3, has been identified and shown to associate with the cytoplasmic domain of CD40. The similarity between a specific region of TRAF3 with regions of TRAF1 and TRAF2 define a “TRAF-C” domain that is necessary and sufficient for CD40 binding and homodimerization.

TRAF2 (C-20) Product Citations
See how others have used TRAF2 (C-20): sc-876 antibody and or TRAF2 (C-20) antibody conjugates.


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TRAF2 (C-20)
Click on image to enlarge
sc-876
Western blot analysis of TRAF2 expression in Jurkat (A,D), A-431 (B,E) and WEHI-231 (C,F) whole cell lysates. Antibodies tested include TRAF2 (C-20): sc-876 (A-C) and TRAF2 (N-19): sc-877 (D-F).
sc-876
TRAF2 (C-20): sc-876. Immunofluorescence staining of methanol-fixed, TRAF2-transfected COS cells showing peripheral cytoplasmic localization.
sc-876
TRAF2 siRNA (h): sc-29509. Western blot analysis of TRAF2 expression in non-transfected control (A) and TRAF2 siRNA transfected (B) HeLa cells. Blot probed with TRAF2 (C-20): sc-876. Actin (I-19): sc-1616 used as specificity and loading control.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in non-transfected: sc-117752 (A), human TRAF2 transfected: sc-114838 (B) and human TRAF2 transfected: sc-115031 (C) 293T whole cell lysates.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in non-transfected: sc-117752 (A) and human TRAF2 transfected: sc-115956 (B) 293T whole cell lysates.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in non-transfected: sc-117752 (A) and human TRAF2 transfected: sc-116412 (B) 293T whole cell lysates.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in non-transfected: sc-117752 (A) and mouse TRAF2 transfected: sc-127697 (B) 293T whole cell lysates.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in Jurkat whole cell lysate.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in non-transfected: sc-117752 (A) and human TRAF2 transfected: sc-172765 (B) 293T whole cell lysates.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in non-transfected: sc-117752 (A) and human TRAF2 transfected: sc-178076 (B) 293T whole cell lysates.
sc-876
TRAF2 (C-20): sc-876. Western blot analysis of TRAF2 expression in non-transfected: sc-117752 (A) and human TRAF2 transfected: sc-178077 (B) 293T whole cell lysates.
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