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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the N-terminus of hSNF2H of human origin
- recommended for detection of hSNF2H of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications, sc-8759 X, 200 µg/0.1 ml
- blocking peptide, sc-8759 P
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Ordering Information
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
SMARCA5 |
8467 |
4q31.21 |
NM_003601 |
O60264
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603375 |
| Mouse |
Smarca5 |
93762 |
8 C2 |
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Q91ZW3
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N/A |
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hSNF2H Background Information The SWI/SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila Isw1, a BRM related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor). |
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hSNF2H (N-17)
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hSNF2H (N-17): sc-8759. Western blot analysis of hSNF2H expression in non-transfected 293T: sc-117752 (A), human hSNF2H transfected 293T: sc-113724 (B) and K-562 (C) whole cell lysates.
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