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home » Transcription Regulators » HMG Antibody / HMG Antibodies » HMG-2 (C-19): sc-8758

HMG-2 (C-19) Antibody: sc-8758

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the C-terminus of HMG-2 of human origin
  • recommended for detection of HMG-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-8758 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-8758 X, 200 µg/0.1 ml
 
Additional HMG Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HMGB2 3148 4q34.1 NM_002129 P26583
 163906
Mouse Hmgb2 97165 8 B2 P30681
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
HMG-2 (C-19) sc-8758 200 µg/ml $279
HMG-2 (C-19) P sc-8758 P
(peptide)
 100 µg/0.5 ml $61
HMG-2 (C-19) sc-8758 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HMG-2 siRNA (h) sc-37984 10 µM $258
HMG-2 siRNA (m) sc-37985 10 µM $258
HMG-2 (h)-PR sc-37984-PR 10 µM $23
HMG-2 (m)-PR sc-37985-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HMG-2 shRNA Plasmid (h) sc-37984-SH 20 µg $520
HMG-2 shRNA Plasmid (m) sc-37985-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HMG-2 shRNA (h) Lentiviral Particles sc-37984-V 200 µl $625
HMG-2 shRNA (m) Lentiviral Particles sc-37985-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 nuclear extract sc-2130 1000 µg $143
HeLa nuclear extract sc-2120 1000 µg $143
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
HMG-2 (h): 293 Lysate sc-110488 100µg/200µl $205

HMG-2 Background Information
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NF˚B family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. HMGB3L1 (
HMG-2 (C-19)
Click on image to enlarge
sc-8758
HMG-2 (C-19): sc-8758. Western blot analysis of HMG-2 expression in K-562 nuclear extract.
sc-8758
HMG-2 (C-19): sc-8758. Western blot analysis of HMG-2 expression in non-transfected: sc-110760 (A) and human HMG-2 transfected: sc-110488 (B) 293 whole cell lysates.
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Datasheets
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