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CIDE-B Antibody (M-19): sc-8734

 |  Datasheet

(Based on data analysis)
  • CIDE-B Antibody (M-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of CIDE-B of mouse origin
  • recommended for detection of CIDE-B of mouse and rat origin by WB, IF and ELISA
  • blocking peptide, sc-8734 P
 

See additional CIDE Antibodies including CIDE, CIDE-A, CIDE-B and CIDE-C.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CIDE-B Antibody (M-19) sc-8734 200 µg/ml $279
CIDE-B (M-19) P sc-8734 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CIDE-B siRNA (m) sc-37442 10 µM $258
CIDE-B (m)-PR sc-37442-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CIDE-B shRNA Plasmid (m) sc-37442-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CIDE-B shRNA (m) Lentiviral Particles sc-37442-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
mouse heart extract sc-2254 500 µg/200 µl $104
mouse liver extract sc-2256 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Cideb 12684 14 C3 O70303
 N/A
 

The DNA fragmentation factor (DFF) is involved in the caspase-3 apoptotic pathway. DFF is composed of two subunits: DFF-45, also designated ICAD (inhibitor of CAD); and CPAN (caspase-activated nuclease), also designated CAD (caspase-activated deoxyribonuclease). CPAN is a DNase that is responsible for DNA degradation during apoptosis. CPAN is inhibited by DFF-45. Caspase-3 acts to dissociate CPAN from DFF-45, allowing CPAN to enter the nucleus and degrade DNA. CIDE-A and CIDE-B have been identified as proteins that share homology with the N-terminal region of DFF-45. Like CPAN, CIDE-A and CIDE-B promote cell death and DNA fragmentation and are inhibited by DFF-45.