JRK Background Information JRK (jerky protein homolog) is also known as JH8 and is a 520 amino acid ortholog of the mouse Jerky protein. JRK is thought to translocate from the nucleolus to many nuclear foci during the S phase and G2 phase of the cell cycle. During mitosis, JRK is localized primarily to the cytoplasm, but may also be present as alternatively spliced isoforms that may be found in several other locations within the cell. The gene encoding JRK maps to human chromosome 8q24.3 and shares a locus with genes that are involved in the pathogenesis of Childhood Absence Epilepsy (CAE), suggesting that JRK may be associated with the development of CAE.
JRK (D-18)
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JRK (D-18): sc-87173. Western blot analysis of JRK expression in non-transfected: sc-117752 (A) and mouse JRK transfected: sc-121163 (B) 293T whole cell lysates.
