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home » Transcription Regulators » NF-1 Antibody / NF-1 Antibodies » NF-1 (N-20): sc-870

NF-1 (N-20) Antibody: sc-870

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of NF-1 of human origin
  • recommended for detection of all NF-1 isoforms of mouse, rat, human and chicken origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-870 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-870 X, 200 µg/0.1 ml
 
Additional NF-1 Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NFIA 4774 1p31.3 NM_005595 Q12857
 600727
Human NFIB 4781 9p23 NM_005596 O00712
 600728
Human NFIC 4782 19p13.3 NM_005597, NM_205843 P08651
 600729
Human NFIX 4784 19p13.13 NM_002501 Q14938
 164005
Mouse Nfia 18027 4 C6 Q02780
 N/A
Mouse Nfib 18028 4 C3 P97863
 N/A
Mouse Nfic 18029 10 C1 P70255
 N/A
Mouse Nfix 18032 8 C3 P70257
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
NF-1 (N-20) sc-870 200 µg/ml $279
NF-1 (N-20) P sc-870 P
(peptide)
 100 µg/0.5 ml $61
NF-1 (N-20) X sc-870 X 200 µg/0.1 ml $279
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NF-1B (m): 293T Lysate sc-125698 100µg/200µl $205
HeLa + PMA nuclear extract sc-2121 1000 µg $143
NF-1 (m2): 293T Lysate sc-122030 100µg/200µl $205
HeLa + PMA Cell Lysate sc-2258 500 µg/200 µl $104
HeLa nuclear extract sc-2120 1000 µg $143
NIH/3T3 nuclear extract sc-2138 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143

NF-1 Background Information
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, å-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

NF-1 (N-20) Product Citations
See how others have used NF-1 (N-20): sc-870 antibody and or NF-1 (N-20) antibody conjugates.


19 total citations
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NF-1 (N-20)
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sc-870
NF-1 (N-20): sc-870. Western blot analysis of NF-1 expression in nuclear extracts prepared from PMA-treated HeLa (A), untreated Jurkat (B) and PMA-treated NIH/3T3 (C) cells.
sc-870
NF-1 (N-20): sc-870. Western blot analysis of NF-1 expression in non-transfected: sc-117752 (A) and mouse NF-1 transfected: sc-122030 (B) 293T whole cell lysates.
sc-870
NF-1 (N-20): sc-870. Western blot analysis of NF-1 expression in HeLa nuclear extract.
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