Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Kinases and Phosphatases » MKP Antibodies » MKP-3 Antibody (C-20): sc-8599

MKP-3 Antibody (C-20): sc-8599

 |  Datasheet

(Based on data analysis)

  • MKP-3 Antibody (C-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of MKP-3 of human origin
  • recommended for detection of MKP-3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-8599 P
  • See 20 citations for MKP-3 Antibody (C-20)
 

See additional MKP Antibodies including MKP-7, MKP-6, MKP-5, MKP-4, MKP-3, MKP-2, MKP-1 and MKP.

Also see MKP Inhibitors for functional analysis of cellular responses to MKP.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
MKP-3 Antibody (C-20) sc-8599 200 µg/ml $279
MKP-3 (C-20) P sc-8599 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MKP-3 siRNA (h) sc-39000 10 µM $258
MKP-3 siRNA (m) sc-39001 10 µM $258
MKP-3 (h)-PR sc-39000-PR 10 µM, 20 µl $23
MKP-3 (m)-PR sc-39001-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MKP-3 shRNA Plasmid (h) sc-39000-SH 20 µg $520
MKP-3 shRNA Plasmid (m) sc-39001-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MKP-3 shRNA (h) Lentiviral Particles sc-39000-V 200 µl $625
MKP-3 shRNA (m) Lentiviral Particles sc-39001-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
MKP-3 (h): 293T Lysate sc-114251 100 µg/200 µl $205
MKP-3 (m): 293T Lysate sc-121681 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DUSP6 1848 12q21.33 NM_001946, NM_022652 Q16828
 602748
Mouse Dusp6 67603 10 D1 Q9DBB1
 N/A
 

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q22-q23 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.

MKP-3 Antibody (C-20) Product Citations
See how others have used MKP-3 Antibody (C-20) and or MKP-3 Antibody (C-20) conjugates.


20 total citations
Loading citations.
 
MKP-3 Antibody (C-20) Data
Click on image to enlarge
sc-8599
MKP-3 (C-20): sc-8599. Western blot analysis of MKP-3 expression in non-transfected: sc-117752 (A) and human MKP-3 transfected: sc-114251 (B) 293T whole cell lysates.
sc-8599
MKP-3 (C-20): sc-8599. Western blot analysis of MKP-3 expression in non-transfected: sc-117752 (A) and mouse MKP-3 transfected: sc-121681 (B) 293T whole cell lysates.
sc-8599
MKP-3 (C-20): sc-8599. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.
Download
Datasheets
Get Adobe Acrobat Reader