IFT88 Antibody (N-17) | Santa Cruz Biotech

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IFT88 Antibody (N-17): sc-84318	\| Datasheet

5 3 (Based on data analysis) 1

IFT88 Antibody (N-17) is a rabbit polyclonal IgG provided at 100 µg/ml
epitope mapping at the N-terminus of IFT88 of human origin
recommended for detection of IFT88 of mouse, rat and human origin by WB, IP, IF and ELISA; non cross-reactive with other IFT family members; also reactive with additional species, including equine, canine, bovine and porcine
blocking peptide, sc-84318 P

See additional IFT Antibodies including IFT, IFT80, IFT20, IFT43, IFT52, IFT81, IFT88, IFT122 and IFT172.

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WB IP IF

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
IFT88 Antibody (N-17)	sc-84318	100 µg/ml	$279
IFT88 (N-17) P	sc-84318 P (peptide)	100 µg/0.5 ml	$61

Species	Gene Name	Gene ID	Chromosome Location	Isoform (mRNA) Accession #	Protein Accession #	OMIM™ Number

Human	IFT88	8100	13q12.11	NM_006531, NM_175605	Q13099	600595
Mouse	Ift88	21821	14 C3	NM_009376	Q61371	N/A

The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. IFT88 (Intraflagellar transport protein 88), also known as TG737 or TTC10 (TPR repeat protein 10), is an 833 amino acid protein that contains 12 TPR repeats and belongs to the TPR family. Expressed in lung, heart, liver, brain, pancreas, kidney and skeletal muscle, IFT88 is thought to interact with other intraflagellar transport proteins and may play a role in the assembly and maintenance of the vertebrate outer segment. Additionally, IFT88 is thought to function as a centrosomal protein that may regulate the G1 to S phase cell cycle transition in non-ciliated cells. Defects in the gene encoding IFT88 may be associated with the pathogenesis of polycystic kidney disease, a genetic disorder that is characterized by the presence of cysts within the kidneys. IFT88 expression is downregulated in hepatocellular carcinomas, suggesting a role for IFT88 in tumor suppression. Multiple isoforms of IFT88 exist due to alternative splicing events.

IFT88 Antibody (N-17) Data

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IFT88 (N-17): sc-84318. Western blot analysis of IFT88 expression in non-transfected: sc-117752 (A) and mouse IFT88 transfected: sc-120963 (B) 293T whole cell lysates.

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IFT88 Antibody (N-17): sc-84318