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IF3 Antibody (G-20): sc-84313

 |  Datasheet

(Based on data analysis)
  • IF3 Antibody (G-20) is a rabbit polyclonal IgG provided at 100 µg/ml
  • epitope mapping within an internal region of IF3 of human origin
  • recommended for detection of IF3 of human origin by WB, IF and ELISA; also reactive with additional species, including equine, bovine and porcine
  • blocking peptide, sc-84313 P
 

See additional IF Antibodies including IF, Mtif3, IF2 and IF3.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
IF3 Antibody (G-20) sc-84313 100 µg/ml $279
IF3 (G-20) P sc-84313 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
IF3 siRNA (h) sc-75319 10 µM $258
IF3 (h)-PR sc-75319-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
IF3 shRNA Plasmid (h) sc-75319-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
IF3 shRNA (h) Lentiviral Particles sc-75319-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MTIF3 219402 13q12.2 Q9H2K0
 n/a
 

IF3 is also known as MTIF3 (mitochondrial translational initiation factor 3), DC38, IF3(mt) or IF-3mt, and is a 278 amino acid protein that is localized to mitochondria. IF3 aids in the initiation of protein synthesis by binding the 28S ribosomal subunit, which is a protein synthesis initiation site. The 28S and 39S ribosomal structures are subunits of the 55S ribosome, whose formation is favored in the absence of IF3, because IF3 allows the subunits to remain in their free form. Altered forms of IF3 may affect IF3’s function, which could alter the availability of mitochondrial encoded proteins, leading to oxidative stress and possibly causing an increased susceptibility to Parkinson’s disease. Polymorphism of the gene encoding IF3 is thought to be associated with Parkinson’s disease.