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home » Cell Cycle Proteins » Cdc Antibody / Cdc Antibodies » Cdc2 p34 (B-6): sc-8395

Cdc2 p34 (B-6) Antibody: sc-8395

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • specific for an epitope mapping between amino acids 2-30 near the N-terminus of Cdc2 p34 of human origin
  • recommended for detection of Cdc2 p34 of mouse, rat and human origin by WB, IP, IF and ELISA
  • blocking peptide, sc-8395 P
 
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Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CDC2 983 10q21.2 NM_001786, NM_033379 P06493
 116940
Mouse Cdc2a 12534 10 B5.3 P11440
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 (B-6) sc-8395 200 µg/ml $279
Cdc2 p34 (B-6) P sc-8395 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 siRNA (h) sc-29252 10 µM $258
Cdc2 p34 siRNA (m) sc-29253 10 µM $258
Cdc2 p34 (h)-PR sc-29252-PR 10 µM $23
Cdc2 p34 (m)-PR sc-29253-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 shRNA Plasmid (h) sc-29252-SH 20 µg $520
Cdc2 p34 shRNA Plasmid (m) sc-29253-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 shRNA (h) Lentiviral Particles sc-29252-V 200 µl $625
Cdc2 p34 shRNA (m) Lentiviral Particles sc-29253-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAMALWA Cell Lysate sc-2234 500 µg/200 µl $104
HeLa nuclear extract sc-2120 1000 µg $143
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
A-431 nuclear extract sc-2122 1000 µg $143
WEHI-231 Whole Cell Lysate sc-2213 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
HeLa + hydroxyurea Cell Lysate sc-24682 500 µg/200 µl $104
Cdc2 p34 (m): 293T Lysate sc-119124 100µg/200µl $205

Cdc2 p34 Background Information
In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.

Cdc2 p34 (B-6) Product Citations
See how others have used Cdc2 p34 (B-6): sc-8395 antibody and or Cdc2 p34 (B-6) antibody conjugates.


15 total citations
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Cdc2 p34 (B-6)
Click on image to enlarge
sc-8395
Cdc2 p34 (B-6): sc-8395. Western blot analysis of Cdc2 p34 expression in A-431 (A) and HeLa (B) nuclear extracts.
sc-8395
Western blot detection of Cdc2 p34 phosphorylation using Saos-2 cells treated with hydroxyurea. Blots were probed with Cdc2 p34 (B-6): sc-8395 (A), p-Cdc2 p34 (Tyr 15)-R: sc-7989-R preincubated with cognate phosphorylated peptide (B) and p-Cdc2 p34 (Tyr 15)-R: sc-7989-R pre-incubated with identical unphosphorylated peptide (C).
sc-8395
Cdc2 p34 siRNA (h): sc-29252. Western blot analysis of Cdc2 p34 expression in non-transfected control (A) and Cdc2 p34 siRNA transfected (B) HeLa cells. Blot probed with Cdc2 p34 (B-6): sc-8395. γ Tubulin (C-11): sc-17787 used as specificity and loading control.
sc-8395
Cdc2 p34 (B-6): sc-8395. Western blot analysis of Cdc2 p34 expression in WEHI-231 whole cell lysate.
sc-8395
Cdc2 p34 (B-6): sc-8395. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
sc-8395
Cdc2 p34 (B-6): sc-8395. Western blot analysis of Cdc2 p34 expression in HeLa (A) and hydroxyurea-treated HeLa (B) whole cell lysates.
sc-8395
Cdc2 p34 (B-6): sc-8395. Western blot analysis of Cdc2 p34 expression in non-transfected 293: sc-110760 (A), human Cdc2 p34 transfected 293: sc-128282 (B) and HeLa (C) whole cell lysates.
sc-8395
Cdc2 p34 (B-6): sc-8395. Western blot analysis of Cdc2 p34 expression in non-transfected 293T: sc-117752 (A), mouse Cdc2 p34 transfected 293T: sc-119124 (B) and K-562 (C) whole cell lysates.
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