BC-2048 Background Information The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. BC-2048, also known as C21orf114, is a 209 amino acid protein that belongs to the transposase 22 family.
BC-2048 (E-17)
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BC-2048 (E-17): sc-83514. Western blot analysis of BC-2048 expression in BJAB (A) and Raji (B) whole cell lysates.
