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home » Tumor Suppressors/Apoptosis » CAD Antibody / CAD Antibodies » CAD (FL-338): sc-8342

CAD (FL-338) Antibody: sc-8342

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-338 representing full length CAD (caspase-activated nuclease) of human origin
  • recommended for detection of CAD of mouse, rat and human origin by WB, IP, IF and ELISA
 
Additional CAD Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DFFB 1677 1p36.32 NM_001004285, NM_001004286, NM_004402 O76075
 601883
Mouse Dffb 13368 4 E2 O54788
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CAD (FL-338) sc-8342 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CAD siRNA (h) sc-29871 10 µM $258
CAD siRNA (m) sc-29872 10 µM $258
CAD (h)-PR sc-29871-PR 10 µM $23
CAD (m)-PR sc-29872-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CAD shRNA Plasmid (h) sc-29871-SH 20 µg $520
CAD shRNA Plasmid (m) sc-29872-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CAD shRNA (h) Lentiviral Particles sc-29871-V 200 µl $625
CAD shRNA (m) Lentiviral Particles sc-29872-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 nuclear extract sc-2130 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143
LNCaP Cell Lysate sc-2231 500 µg/200 µl $104
Jurkat + PMA nuclear extract sc-2133 1000 µg $143

CAD Background Information
The Ced/ICE or caspase family of cysteine proteases plays a pivotol role in mediating apoptosis through the proteolysis of specific targets. Among the targets are poly(ADP-ribose) polymerase (PARP), Gelsolin, ICAD (inhibitor of CAD, also designated DFF-45) and the nuclear lamins. CAD (caspase-activated deoxyribonuclease), also designated CPAN (caspase-activated nuclease) and DFF40, is a DNase that is responsible for DNA degradation during apoptosis. Caspase-3 acts to dissociate CAD from ICAD, allowing CAD to enter the nucleus and degrade DNA.

CAD (FL-338) Product Citations
See how others have used CAD (FL-338): sc-8342 antibody and or CAD (FL-338) antibody conjugates.


5 total citations
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CAD (FL-338)
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sc-8342
CAD (FL-338): sc-8342. Western blot analysis of CAD expression in RAW 309 Cr.1 whole cell lysate.
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