 |
- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 204-372 of Cdk9 of human origin
- recommended for detection of Cdk9 (also designated PITALRE) of mouse, rat and human origin by WB, IP, IF IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- TransCruz reagent for ChIP application, sc-8338 X, 200 µg/0.1 ml
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
CDK9 |
1025 |
9q34.11 |
NM_001261 |
P50750
|
603251 |
| Mouse |
Cdk9 |
107951 |
2 B |
|
Q99J95
|
N/A |
| |
Cdk9 Background Information
A family of proteins designated cyclin dependent kinases (Cdks) are critical regulators of cell cycle progression. Cdk family members, including Cdc2 p34, Cdk1–9, PISSLRE, KKIALRE, PITSLRE, and PCTAIRE 1–3 are constitutively expressed throughout the cell cycle. Cdc2 p34 activity peaks during mitosis and Cdk2 activity rises in late G1 or early S phase. Cdk4 and Cdk6 are critically involved in G1 to S phase progression. The functions of Cdk3, Cdk5b, PISSLRE, KKIALRE and PCTAIRE 1–3 are less well defined. Cdk9 (also designated PITALRE) has been shown to specifically phosphorylate the retinoblastoma protein. The more recently cloned Drosophila protein, P-TEFb, is thought to be the homolog of mammalian PITALRE. P-TEFb has been shown to be required for HIV Tat transcriptional activation .
| Cdk9 (H-169) Product Citations |
See how others have used Cdk9 (H-169): sc-8338 antibody and or Cdk9 (H-169) antibody conjugates.
20 total citations Loading citations.
|
| |
|
|
|
Cdk9 (H-169)
Click on image to enlarge
|
|
Cdk9 (H-169): sc-8338. Western blot analysis of human recombinant Cdk9 fusion protein.
Cdk9 (H-169): sc-8338. Western blot analysis of Cdk9 expression in NIH/3T3 whole cell lysate.
Cdk9 (H-169): sc-8338. Western blot analysis of Cdk9 expression in non-transfected 293: sc-110760 (A), human Cdk9 transfected 293: sc-110469 (B) and HL-60 (C) whole cell lysates. Cdk9 (H-169): sc-8338. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
Cdk9 (H-169): sc-8338. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining of cells in tubules.
|
|
Download
|
|
