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- rabbit polyclonal IgG, 200 µg/ml; also available as goat IgG, 200 µg/ml, sc-832-G
- epitope mapping within an internal region of Bak of human origin
- recommended for detection of Bak of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-832 P
- agarose conjugate for IP studies, sc-832 AC, 500 µg/0.25 ml agarose
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
BAK1 |
578 |
6p21.31 |
NM_001188 |
Q16611
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600516 |
| Mouse |
Bak1 |
12018 |
17 A3.3 |
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O08734
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N/A |
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Bak Background Information
The Bcl-2 family of proteins is characterized by its ability to modulate cell death (apoptosis) under a broad range of physiologic conditions (1,2). Bcl-2 and several related proteins function to inhibit apoptosis (3-5), while other members of the Bcl-2 family, such as Bax, accelerate death under various conditions (6,7). One member of the Bcl-2 family, designated Bak, functions primarily to enhance apoptotic cell death following appropriate activating signals (1,2) and, in addition, counteracts the protection from apoptosis provided by Bcl-2 (1,2). Expression of Bak is widespread in a broad range of cells, including various long-lived, terminally differentiated cell types, suggesting that its cell-death-inducing activity is broadly distributed and that the regulation of inhibitors of apoptosis may represent an important determinant of tissue-specific modulation of apoptosis (1,2).
| Bak (G-23) Product Citations |
See how others have used Bak (G-23): sc-832 antibody and or Bak (G-23) antibody conjugates.
75 total citations Loading citations.
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Bak (G-23)
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Bak (G-23): sc-832. Western blot analysis of Bak expression in A-431 (A), HeLa (B) and MOLT-4 (C) whole cell lysates.
Bak (G-23): sc-832. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining.
Bak (G-23): sc-832. Western blot analysis of Bak expression in non-transfected: sc-117752 (A) and human Bak transfected: sc-111918 (B) 293T whole cell lysates. Bak (G-23): sc-832. Western blot analysis of Bak expression in non-transfected 293T: sc-117752 (A), human Bak transfected 293T: sc-111918 (B) and HeLa (C) whole cell lysates. |
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