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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 35-205 representing mature tumor necrosis factor beta (TNFβ) of human origin
- recommended for detection of TNFβ of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
LTA |
4049 |
6p21.33 |
NM_000595 |
P01374
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153440 |
| Mouse |
Lta |
16992 |
17 B1 |
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P09225
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N/A |
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TNFβ Background Information
Tumor necrosis factor b (TNFb), also known as lymphotoxin, is a pleiotropic cytokine. TNFa, also known as cachectin, is a smaller cytokine that binds to the same receptors, producing a vast array of effects similar to those of TNFb. TNFb and TNFa share 30% amino acid homology and have similar biological activities. TNFb is produced by activated lymphocytes, including CD4(+) T helper cell type 1 lymphocytes, CD8(+) lymphocytes and certain B lymphoblastoid cell lines. TNFa is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFa and TNFb can modulate many immune and inflammatory functions, while having the ability to inhibit tumor growth. Target tumor cells must express TNF receptors 1 and 2 to be killed, with the p55 receptor mediating the cytotoxic response.
| TNFβ (H-171) Product Citations |
See how others have used TNFβ (H-171): sc-8302 antibody and or TNFβ (H-171) antibody conjugates.
3 total citations Loading citations.
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TNFβ (H-171)
Click on image to enlarge
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TNFβ (H-171): sc-8302. Western blot analysis of human recombinant TNFβ (A,B).
TNFβ (H-171): sc-8302. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse spleen tissue showing extracellular localization.
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