epitope mapping within an internal region of GlcNAc kinase
of human origin
recommended for detection of GlcNAc kinase of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
GlcNAc kinase Background Information GlcNAc kinase, also known as GNK or NAGK (N-acetylglucosamine kinase), is a 344 amino acid homodimeric protein that is ubiquitously expressed. Belonging to the sugar kinase/Hsp70/actin superfamily and the eukaryotic-type N-acetylglucosamine kinase family, GlcNAc kinase converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. GlcNAc kinase is considered a salvage enzyme of amino sugar metabolism in mammals and predominately produces the beta anomer of phosphorylated sugars. It is suggested that GlcNAc kinase has ManNAc kinase activity.
GlcNAc kinase (D-17)
Click on image to enlarge
GlcNAc kinase (D-17): sc-82612. Western blot analysis of GlcNAc kinase expression in non-transfected 293T: sc-117752 (A), mouse GlcNAc kinase transfected 293T: sc-120498 (B) and HeLa (C) whole cell lysates.
