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ACOT4 Antibody (D-19): sc-82481

 |  Datasheet

(Based on data analysis)
  • ACOT4 Antibody (D-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of ACOT4 of mouse origin
  • recommended for detection of ACOT4 of mouse and rat origin by WB, IF and ELISA; non cross-reactive with family members ACOT1/2 or ACOT2
  • blocking peptide, sc-82481 P
 

See additional ACOT Antibodies including ACOT, ACOT1, ACOT2, ACOT4, ACOT6, ACOT7, ACOT8, ACOT9, ACOT10, ACOT11, ACOT3, ACOT5 and ACOT12.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ACOT4 Antibody (D-19) sc-82481 200 µg/ml $279
ACOT4 (D-19) P sc-82481 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ACOT4 siRNA (m) sc-72438 10 µM $258
ACOT4 (m)-PR sc-72438-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ACOT4 shRNA Plasmid (m) sc-72438-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ACOT4 shRNA (m) Lentiviral Particles sc-72438-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Acot4 171282 12 D1 Q8BWN8
 N/A
 

Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. Specifically, several ACOT proteins, including ACOT1, ACOT2 and ACOT 4, catalyze the conversion of palmitoyl-CoA and water to free CoA and palmitate. ACOT4, also designated peroxisomal acyl coenzyme A thioester hydrolase Ib (PTEIB), is a 421 amino acid protein that is localized to the peroxisome. Highest expression levels of ACOT4 are found in liver and kidney with weaker expression in placenta, heart, and muscle. ACOT4 appears to have obtained the functionality of three mouse genes, ACOT3, ACOT4 and ACOT5, acting on substrates of succinyl-CoA and medium to long chain acyl-CoAs.