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USP48 Antibody (I-19): sc-82406

 |  Datasheet

(Based on data analysis)

  • USP48 Antibody (I-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of USP48 of human origin
  • recommended for detection of USP48 of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with isoforms USP48-5 or USP48-6; also reactive with additional species, including equine, canine, bovine and avian
  • blocking peptide, sc-82406 P
 

See additional USP Antibodies including USP, USP1, USP17, USP27, USP46, USP2, USP3, USP4, USP5, USP6, USP9, USP9X, USP9Y, USP10, USP11, USP12, USP13, USP14, USP15, USP18, USP19, USP20, USP21, USP22, USP24, USP25, USP26, USP28, USP29, USP30, USP31, USP32, USP33, USP34, USP35, USP36, USP37, USP38, USP39, USP40, USP42, USP43, USP44, USP45, USP47, USP48, USP49, USP50, USP51, USP52, USP53, USP54 and USP17L4.

Also see USP Inhibitors for functional analysis of cellular responses to USP.


Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
USP48 Antibody (I-19) sc-82406 200 µg/ml $279
USP48 (I-19) P sc-82406 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
USP48 siRNA (h) sc-76865 10 µM $258
USP48 siRNA (m) sc-76866 10 µM $258
USP48 (h)-PR sc-76865-PR 10 µM, 20 µl $23
USP48 (m)-PR sc-76866-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
USP48 shRNA Plasmid (h) sc-76865-SH 20 µg $520
USP48 shRNA Plasmid (m) sc-76866-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
USP48 shRNA (h) Lentiviral Particles sc-76865-V 200 µl $625
USP48 shRNA (m) Lentiviral Particles sc-76866-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human USP48 84196 1p36.12 Q86UV5
n/a
Mouse Usp48 170707 4 D3 Q3V0C5
N/A
 


The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP48 (ubiquitin specific peptidase 48), also known as USP31 or RAP1GA1 is a widely expressed 1,035 amino acid protein that belongs to the peptidase C19 family of proteins. Containing three DUSP domains and one ubiquitin-like domain, USP48 functions as a deubiquitinating enzyme that cleaves ubiquitin residues from both ubiquitinylated proteins and ubiquitin-fused precursors, thereby saving these proteins from proteasomal degradation. By reversing the ubiquitination of proteins such as TRAF2 and TRAF6, USP48 plays an important role in the regulation of NF˚B activation. Seven isoforms of USP48 are expressed due to alternative splicing events.