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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the N-terminus of Fhit of human origin
- recommended for detection of Fhit of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
- blocking peptide, sc-8215 P
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
FHIT |
2272 |
3p14.2 |
NM_002012 |
P49789
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601153 |
| Mouse |
Fhit |
14198 |
14 A1 |
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O89106
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N/A |
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Fhit Background Information
FHIT, a candidate tumor suppressor gene, contains the FRA3B common fragile site and is highly susceptible to carcinogen damage. The pattern of mutational inactivation seen with the FHIT gene is unique compared with other known tumor suppressors. FHIT gene structure and expression have been shown to be altered in esophageal, head, neck, lung, gastric, breast, and cervical carcinomas. It has been demonstrated that FHIT exon loss is associated with smoking duration or asbestos exposure. The FHIT protein is a member of the histidine triad (HIT) superfamily and functions as a dinucleoside 5’,5’’’-P1,P3-triphosphate hydrolase.
| Fhit (N-19) Product Citations |
See how others have used Fhit (N-19): sc-8215 antibody and or Fhit (N-19) antibody conjugates.
1 total citations Loading citations.
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Fhit (N-19)
Click on image to enlarge
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Fhit (N-19): sc-8215. Western blot analysis of Fhit expression in non-transfected: sc-117752 (A) and human Fhit transfected: sc-114836 (B) 293T whole cell lysates. Fhit (N-19): sc-8215. Western blot analysis of Fhit expression in non-transfected: sc-117752 (A) and mouse Fhit transfected: sc-120253 (B) 293T whole cell lysates. |
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