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ENSA Antibody (L7Q): sc-81883

 |  Datasheet

(Based on data analysis)

  • ENSA Antibody (L7Q) is a mouse monoclonal IgG2a provided at 50 µg/0.5 ml
  • recommended for detection of endosulfine alpha of human origin by WB, IP and ELISA
 

See additional ENSA Antibodies including ARPP-19 and ENSA.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ENSA Antibody (L7Q) sc-81883 50 µg/0.5 ml $295
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ENSA siRNA (h) sc-78564 10 µM $258
ENSA (h)-PR sc-78564-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ENSA shRNA Plasmid (h) sc-78564-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ENSA shRNA (h) Lentiviral Particles sc-78564-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ENSA 2029 1q21.2 O43768
 603061
 

ATP-dependent potassium K(ATP) channels regulate the polarity of the cell membrane, which affects cell metabolism and insulin secretion. When ATP levels risein response to an increased rate of glucose metabolism, the K(ATP) channels close, which stimulates the cells to secrete Insulin. K(ATP) channels are composed of 2 structurally unrelated subunits; a Kir6.0 subfamily component and a sulfonylurea receptor (SUR) component. ENSA (Alpha-endosulfine), also known as ARPP-19e, is a 121 amino acid endogenous ligand for SUR. ENSA inhibits the binding of sulfonylurea to the SUR component of the K(ATP) channel, thereby reducing channel activity and stimulating the secretion of Insulin. ENSA is localized to the cytoplasm and widely expressed in tissues, with high expression in brain and muscle and low expression in pancreas. ENSA is phosphorylated by PKA and exists as 2 isoforms, designated alpha and beta, produced by alternative splicing.

ENSA Antibody (L7Q) Data
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sc-81883
ENSA (L7Q): sc-81883. Western blot analysis of ENSA expression in COLO 320 HSR whole cell lysate.
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