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PKC θ Antibody (1C2): sc-81534

 |  Datasheet

(Based on data analysis)

  • PKC θ Antibody (1C2) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
  • raised against a synthetic peptide corresponding to the C-terminal region of PKC θ of human origin
  • recommended for detection of PKC θ of h and r origin by WB and IP
  • See 2 citations for PKC θ Antibody (1C2)
 

See additional PKC Antibodies including PKC, PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC eta, PKC gamma, PKC iota, PKC lambda, PKC mu, PKC nu, PKC omega, PKC theta, PKC zeta and Pkc1.

Also see PKC theta Inhibitors for functional analysis of cellular responses to PKC theta and PKC theta.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PKC θ Antibody (1C2) sc-81534 50 µg/0.5 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PKC θ siRNA (h) sc-36252 10 µM $258
PKC θ siRNA (r) sc-270095 10 µM $258
PKC θ (h)-PR sc-36252-PR 10 µM, 20 µl $23
PKC θ (r)-PR sc-270095-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PKC θ shRNA Plasmid (h) sc-36252-SH 20 µg $520
PKC θ shRNA Plasmid (r) sc-270095-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PKC θ shRNA (h) Lentiviral Particles sc-36252-V 200 µl $625
PKC θ shRNA (r) Lentiviral Particles sc-270095-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MOLT-4 Cell Lysate sc-2233 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
rat thymus extract sc-2401 500 µg/200 µl $104
rat brain extract sc-2392 500 µg/200 µl $104
SW480 Cell Lysate sc-2219 500 µg/200 µl $104
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
T-47D Cell Lysate sc-2293 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PRKCQ 5588 10p15.1 NM_006257 Q04759
600448
 


Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (å, ∫I, ∫II, ©, ∂, é, Ω, h, †, λ/î, µ and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC ∂ and é are independent of Ca++. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.

PKC θ Antibody (1C2) Product Citations
See how others have used PKC θ Antibody (1C2) and or PKC θ Antibody (1C2) conjugates.


2 total citations
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PKC θ Antibody (1C2) Data
Click on image to enlarge
Western blot analysis of PKC θ phosphorylation in untreated (A,C), PMA treated (B,E) and PMA and lambda protein phosphatase treated (C,F) Jurkat whole cell lysates. Antibodies tested include p-PKC θ (A-11): sc-271922 (A,B,C) and PKC θ (1C2): sc-81534 (D,E,F).
PKC θ (1C2): sc-81534. Western blot analysis of PKC θ expression in serum starved A431 (A), SW480 (B), SW620 (C), HT29 (D), MCF7 (E), MDA-MB-231 (F) and T-47D (G) whole cell lysates.
Western blot analysis of PKC θ phosphorylation in untreated (A,D), PMA treated (B,E) and PMA and lambda protein phosphatase treated (C,F) Jurkat whole cell lysates. Antibodies tested include p-PKC θ (Thr 538): sc-33885 (A,B,C) and PKC θ (1C2): sc-81534 (D,E,F).
Western blot analysis of PKC θ phosphorylation in untreated (A,D), PMA treated (B,E) and PMA and lambda protein phosphatase treated (C,F) Jurkat whole cell lysates. Antibodies tested include p-PKC θ (A-4): sc-271920 (A,B,C) and PKC θ (1C2): sc-81534 (D,E,F).
Western blot analysis of PKC θ phosphorylation in untreated (A,D), PMA treated (B,E) and PMA and lambda protein phosphatase (sc-200312A) treated (C,F) Jurkat whole cell lysates. Antibodies tested include p-PKC θ (Thr 538): sc-33885 (A,B,C) and PKC θ (1C2): sc-81534 (D,E,F).
Western blot analysis of PKC θ phosphorylation in untreated (A,D), PMA treated (B,E) and PMA and lambda protein phosphatase (sc-200312A) treated (C,F) Jurkat whole cell lysates. Antibodies tested include p-PKC θ (pT538.19): sc-136017 (A,B,C) and PKC θ (1C2): sc-81534 (D,E,F).
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