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DDX3 Antibody (2253C5a): sc-81247

 |  Datasheet

(Based on data analysis)

  • DDX3 Antibody (2253C5a) is a mouse monoclonal IgG1 provided at 100 µg/ml
  • raised against a recombinant protein corresponding to the N-terminal region of DDX3 of human origin
  • recommended for detection of DDX3x of mouse, rat and human origin by WB and IP
 

See additional DDX Antibodies including DDX, DDX1, DDX12, DDX19A, DDX26B, DDX3L, DDX3, DDX3X, DDX3Y, DDX8, DDX10, DDX11, DDX15, DDX16, DDX17, DDX18, DDX19, DDX21, DDX23, DDX24, DDX25, DDX27, DDX28, DDX29, DDX30, DDX31, DDX32, DDX33, DDX34, DDX35, DDX36, DDX37, DDX38, DDX40, DDX41, DDX42, DDX43, DDX46, DDX47, DDX49, DDX50, DDX51, DDX52, DDX54, DDX55, DDX56, DDX57, DDX59 and DDX60.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
DDX3 Antibody (2253C5a) sc-81247 100 µg/ml $295
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DDX3X siRNA (h) sc-77108 10 µM $258
DDX3X siRNA (m) sc-77109 10 µM $258
DDX3X (h)-PR sc-77108-PR 10 µM, 20 µl $23
DDX3X (m)-PR sc-77109-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DDX3X shRNA Plasmid (h) sc-77108-SH 20 µg $520
DDX3X shRNA Plasmid (m) sc-77109-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DDX3X shRNA (h) Lentiviral Particles sc-77108-V 200 µl $625
DDX3X shRNA (m) Lentiviral Particles sc-77109-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DDX3X 1654 Xp11.4 NM_001356, XM_001129278 O00571
 300160
Mouse Ddx3x 13205 X A1.1 Q62167
 N/A
 

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX3 (DEAD box polypeptide 3) is involved in RNA metabolism. Two DDX3 paralogs are found in humans; DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections.
DDX3 Antibody (2253C5a) Data
Click on image to enlarge
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DDX3 (2253C5a): sc-81247 Western Blot analysis of human recombinant DDX3 fusion protein.
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DDX3 (2253C5a): sc-81247 Western Blot analysis of DDX3 expression in HeLa whole cell lysate.
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DDX3 (2253C5a): sc-81247 Western Blot analysis of DDX3 expression in NIH/3T3 whole cell lysate.
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DDX3 (2253C5a): sc-81247 Western Blot analysis of DDX3 expression in F2408 whole cell lysate.
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DDX3 (2253C5a): sc-81247. Western blot analysis of DDX3 expression in Jurkat (A) and PC-12 (B) whole cell lysates and K-562 nuclear extract (C).
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Datasheets
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