B-Myb Antibody (MYBAD10A): sc-81192
- B-Myb Antibody (MYBAD10A) is a mouse monoclonal IgG1, cited in 4 publications, provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of B-Myb of human origin
- recommended for detection of B-Myb of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for B-Myb Antibody (MYBAD10A). This work is in progress.
B-Myb Antibody (MYBAD10A) is a mouse monoclonal IgG1 antibody that detects B-Myb in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). B-Myb plays a crucial role as a transcription factor, particularly in the regulation of genes involved in cell cycle progression and differentiation. B-Myb expression remains low or undetectable in quiescent cells but significantly increases during the G1/S-phase transition following mitogenic stimulation. This regulation allows B-Myb to facilitate the transition from a resting state to active cell division, thereby influencing cellular proliferation. Studies have indicated that B-Myb can rescue cells from p53-induced G1 arrest mediated by p21, highlighting B-Myb′s importance in overcoming cell cycle checkpoints that would otherwise prevent proliferation in response to stress signals. Anti-B-Myb antibody (MYBAD10A) serves as an essential tool for researchers investigating the dynamics of cell cycle regulation and the molecular mechanisms underlying hematopoietic cell transformation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
B-Myb Antibody (MYBAD10A) | sc-81192 | 100 µg/ml | $333.00 |