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Met Antibody (B-2): sc-8057

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  • Met Antibody (B-2) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 1350-1379 at the C-terminus of c-Met p140 of mouse origin
  • recommended for detection of Met of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
  • agarose (sc-8057 AC), 500 µg/0.25 ml agarose in 1 ml, for IP; HRP (sc-8057 HRP), 200 µg/ml, for WB, IHC(P) and ELISA; phycoerythrin (sc-8057 PE), fluorescein (sc-8057 FITC), Alexa Fluor® 488 (sc-8057 AF488) or Alexa Fluor® 647 (sc-8057 AF647), 200 µg/ml, for IF, IHC(P) and FCM
  • Blocking peptide available for competition studies, sc-8057 P, (100 µg peptide in 0.5 ml PBS containing < 0.1% sodium azide and 0.2% BSA).
  • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP): sc-516102, m-IgGκ BP-FITC: sc-516140, m-IgGκ BP-PE: sc-516141, or m-IgGκ BP-B: sc-516142, our highly recommended recombinant alternatives to conventional secondary anti-mouse IgG reagents.
  • See 66 citations for Met Antibody (B-2)
 

See additional Met Antibodies.

Also see chemical Met Inhibitors for functional analysis of cellular responses to Met.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Met Antibody (B-2) sc-8057 200 µg/ml $279
Met (B-2) P sc-8057 P
(peptide)
100 µg/0.5 ml $61
Met Antibody (B-2) AC sc-8057 AC 500 µg/ml, 25% ag $366
Met Antibody (B-2) Alexa Fluor® 488 sc-8057 AF488 200 µg/ml $314
Met Antibody (B-2) Alexa Fluor® 647 sc-8057 AF647 200 µg/ml $314
Met Antibody (B-2) FITC sc-8057 FITC 200 µg/ml $292
Met Antibody (B-2) HRP sc-8057 HRP 200 µg/ml $279
Met Antibody (B-2) PE sc-8057 PE 200 µg/ml $303
 CRISPR KO, HDR and Nickase Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Met CRISPR/Cas9 KO Plasmid (h) sc-400101 20 µg $345
Met HDR Plasmid (h) sc-400101-HDR 20 µg $385
Met Double Nickase Plasmid (h) sc-400101-NIC 20 µg $355
Met Double Nickase Plasmid (h2) sc-400101-NIC-2 20 µg $355
Met CRISPR/Cas9 KO Plasmid (m) sc-421635 20 µg $345
Met HDR Plasmid (m) sc-421635-HDR 20 µg $385
Met Double Nickase Plasmid (m) sc-421635-NIC 20 µg $355
Met Double Nickase Plasmid (m2) sc-421635-NIC-2 20 µg $355
 CRISPR Activation Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Met CRISPR Activation Plasmid (h) sc-400101-ACT 20 µg $345
Met CRISPR Activation Plasmid (h2) sc-400101-ACT-2 20 µg $345
Met Lentiviral Activation Particles (h) sc-400101-LAC 200 µl $395
Met Lentiviral Activation Particles (h2) sc-400101-LAC-2 200 µl $395
Met CRISPR Activation Plasmid (m) sc-421635-ACT 20 µg $345
Met CRISPR Activation Plasmid (m2) sc-421635-ACT-2 20 µg $345
Met Lentiviral Activation Particles (m) sc-421635-LAC 200 µl $395
Met Lentiviral Activation Particles (m2) sc-421635-LAC-2 200 µl $395
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Met siRNA (m) sc-35924 10 µM $258
Met (m)-PR sc-35924-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Met shRNA Plasmid (m) sc-35924-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Met shRNA (m) Lentiviral Particles sc-35924-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Met 17295 6 A2 NM_008591 P16056
N/A
 


The c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a transmembrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibit transforming activity. Tyrosine phosphorylation of apparently normal Met protein has also been observed in certain human gastric carcinoma cell lines . The c-Met gene product has been identified as the cell-surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.

Met Antibody (B-2) Product Reviews

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Met Antibody (B-2) Product Citations
See how others have used Met Antibody (B-2) and or Met Antibody (B-2) conjugates.


66 total citations
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Met Antibody (B-2) Data
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Met (B-2): sc-8057. Western blot analysis of Met expression in LADMAC whole cell lysate.
Met (B-2): sc-8057. Immunoperoxidase staining of formalin fixed, paraffin-embedded rat kidney tissue showing membrane and cytoplasmic staining of cells in glomeruli and endothelial cells.
Met (B-2): sc-8057. Western blot analysis of Met expression in EOC 20 whole cell lysate (A) and rat pancreas tissue extract (B).
Met (B-2): sc-8057. Immunoperoxidase staining of formalin fixed, paraffin-embedded rat lung tissue showing cytoplasmic staining of pneumocytes and macrophages and membrane and cytoplasmic staining of endothelial cells.
Met (B-2): sc-8057. Western blot analysis of Met expression in LADMAC whole cell lysate.
Met (B-2): sc-8057. Immunoperoxidase staining of formalin fixed, paraffin-embedded rat liver tissue showing membrane and cytoplasmic staining of sinusoidal endothelial cells.
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