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home » Growth Factors and Hormones » VEGF Antibody / VEGF Antibodies » VEGF-B (J-14I): sc-80442

VEGF-B (J-14I) Antibody: sc-80442

  |  Datasheet
  • mouse monoclonal IgG1, 100µg/ml
  • raised against full length recombinant VEGF-B167 of human origin
  • recommended for detection of VEGF-B167 and VEGF-B186 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional VEGF Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human VEGFB 7423 11q13.1 NM_003377 P49765
 601398
Mouse Vegfb 22340 19 A P49766
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
VEGF-B (J-14I) sc-80442 100 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
VEGF-B siRNA (h) sc-39840 10 µM $258
VEGF-B siRNA (m) sc-39841 10 µM $258
VEGF-B (h)-PR sc-39840-PR 10 µM $23
VEGF-B (m)-PR sc-39841-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
VEGF-B shRNA Plasmid (h) sc-39840-SH 20 µg $520
VEGF-B shRNA Plasmid (m) sc-39841-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
VEGF-B shRNA (h) Lentiviral Particles sc-39840-V 200 µl $625
VEGF-B shRNA (m) Lentiviral Particles sc-39841-V 200 µl $625

VEGF-B Background Information
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs). The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-C and VEGF-D, all of which may exhibit angiogenic function in vivo. VEGF-B, which exists as two alternatively spliced isoforms known as VEGF-B167 and VEGF-B186, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF. VEGF-C binds to and specifically activates Flt-4 and Flk-1. The genes that encode human VEGF-B and VEGF-C have been localized to chromosomes 11q13 and 4q34, respectively.
VEGF-B (J-14I)
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sc-80442
VEGF-B (J-14I): sc-80442. Western blot analysis of VEGF-B expression in PC-3 whole cell lysate.
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