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- mouse monoclonal IgG1; 200 µg/ml
- raised against amino acids 1-159 mapping at the N-terminus of IFI-16 of human origin
- recommended for detection of IFI-16 of human origin by WB, IP, IHC(P), ELISA and indirect FCM using FITC-conjugated goat anti-mouse IgG: sc-2010
- agarose conjugate for IP studies, sc-8023 AC, 500 µg/0.25 ml agarose
- fluorescein conjugate for intracellular FCM, sc-8023 FITC, 100 tests
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
IFI16 |
3428 |
1q23.1 |
NM_005531 |
Q16666
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147586 |
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IFI-16 Background Information
Interferon-inducible proteins include IFI-202, IFI-203, IFI-204 and D3, and are encoded by six or more structurally related and IFN-inducible mouse genes mapping at the q21-q23 region of chromosome 1. The proteins encoded by these genes have homologous 200 amino acid segments. IFI-202 is a primarily nuclear phosphoprotein which inhibits cell growth, in part by modulating transcriptional activity of NFkB, E2F, AP-1 and p53. Two related human proteins, MNDA (myeloid cell nuclear differentiation antigen) and IFI-16, have also been described. Expression of MNDA has been observed specifically in cells of the granulocyte-macrophage lineage. IFI-16 is constitutively expressed in various T and B cell lines and can be induced by IFN-g in HL-60 cells. At least four of the gene-200 cluster of IFN-inducible proteins, IFI-202, IFI-204, MNDA and IFI-16, are localized in the nucleus.
| IFI-16 (1G7) Product Citations |
See how others have used IFI-16 (1G7): sc-8023 antibody and or IFI-16 (1G7) antibody conjugates.
9 total citations Loading citations.
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IFI-16 (1G7)
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IFI-16 (1G7): sc-8023. Western blot analysis of IFI-16 expression in BJAB whole cell lysate.
IFI-16 (1G7): sc-8023. Immunofluorescence staining of methanol-fixed Jurkat cells (A), immunoperoxidase staining of formalin-fixed, paraffin-embedded normal human tonsil (B) and immunofluorescence staining of methanol-fixed BJAB cells (C) showing nuclear localization.
IFI-16 (1G7): sc-8023. Indirect, intracellular FCM analysis of fixed and permeabilized Jurkat cells stained with IFI-16 (1G7), followed by FITC-conjugated goat anti-mouse IgG: sc-2010. Black line histogram represents the isotype control, normal mouse IgG 1: sc-3877. IFI-16 (1G7): sc-8023. Western blot analysis of IFI-16 expression in non-transfected: sc-110760 (A) and human IFI-16 transfected: sc-113241 (B) whole cell lysates. IFI-16 (1G7): sc-8023. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing nuclear staining of lymphoid cells (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
IFI-16 (1G7) FITC: sc-8023 FITC. Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal mouse IgG 1: sc-2855. |
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