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- mouse monoclonal IgG2b, 100µg/ml
- raised against the active and pro forms of MMP-7 of human origin
- recommended for detection of MMP-7 of human origin by WB, IP, IF and IHC(P)
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Ordering Information
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
MMP7 |
4316 |
11q22.2 |
NM_002423 |
P09237
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178990 |
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MMP-7 Background Information
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-7 (also designated Pump-1, matrilysin or uterine metalloproteinase) degrades casein, fibronectin and gelatin types I, III, IV and V. MMP-7 mRNA is produced exclusively by epithelial cells in mouse and expression is restricted to specific organs, suggesting that in addition to matrix degradation and remodeling, MMP-7 may be involved in the differentiated function of these organs. |
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MMP-7 (JL07)
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MMP-7 (JL07): sc-80205. Western blot analysis of MMP-7 expression in non-transfected 293T: sc-117752 (A), human MMP-7 transfected 293T: sc-158741 (B) and HeLa (C) whole cell lysates. MMP-7 (JL07): sc-80205. Western blot analysis of MMP-7 expression in A-431 (A), PC-3 (B) and MIA PaCa-2 (C) whole cell lysates.
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