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home » Structural Proteins » Cytokeratin Antibody / Cytokeratin Antibodies » pan-Cytokeratin (C11): sc-8018

pan-Cytokeratin (C11) Antibody: sc-8018

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against keratin-enriched human epidermoid carcinoma cell line A-431
  • recommended for detection of cytokeratins 4, 5, 6, 8, 10, 13 and 18 of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA
  • phycoerythrin conjugate for intracellular FCM, sc-8018 PE, 100 tests
  • agarose conjugate for IP studies, sc-8018 AC, 500 µg/0.25 ml agarose
  • HRP conjugate, sc-8018 HRP, 200 µg/ml
 
Additional Cytokeratin Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   FCM   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human KRT10 3858 17q21.2 NM_000421 P13645
 607602
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
pan-Cytokeratin (C11) sc-8018 200 µg/ml $279
pan-Cytokeratin (C11) AC sc-8018 AC 500µg/ml, 25%ag $366
pan-Cytokeratin (C11) HRP sc-8018 HRP 200 µg/ml $279
pan-Cytokeratin (C11) PE sc-8018 PE 100 tests in 2ml $303
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
T24 Cell Lysate sc-2292 500 µg/200 µl $104
Cytokeratin 10 (h): 293T Lysate sc-113858 100µg/200µl $205
SW480 Cell Lysate sc-2219 500 µg/200 µl $104

pan-Cytokeratin Background Information
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue (1,2). Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells (3,4). Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors (5,6). For example, cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas (5-6).

pan-Cytokeratin (C11) Product Citations
See how others have used pan-Cytokeratin (C11): sc-8018 antibody and or pan-Cytokeratin (C11) antibody conjugates.


14 total citations
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pan-Cytokeratin (C11)
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sc-8018
pan-Cytokeratin (C11): sc-8018. Western blot analysis of Cytokeratin protein expression in MCF7 (A), HeLa (B) and A-431 (C) whole cell lysates.
sc-8018
pan-Cytokeratin (C11) PE: sc-8018 PE. Intracellular FCM analysis of fixed and permeabilized HeLa cells. Black line histogram represents the isotype control, normal mouse IgG1: sc-2866.
sc-8018
pan-Cytokeratin (C11): sc-8018. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver carcinoma tissue showing cytoskeletal localization of Cytokeratin protein (A). Immunofluorescence staining of methanol-fixed A-431 cells showing cytoskeletal fluorescein immunostaining of Cytokeratin proteins. Note also nuclear rhodamine immunostaining with p53 (FL-393): sc-6243 (B).
sc-8018
pan-Cytokeratin (C11): sc-8018. Western blot analysis of pan-Cytokeratin expression in HeLa whole cell lysate.
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