Date published: 2025-10-15

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GRK 1 Antibody (G-8): sc-8004

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Datasheets
  • GRK 1 Antibody (G-8) is a mouse monoclonal IgG1 κ, cited in 11 publications, provided at 200 µg/ml
  • raised against full-length GRK 1 of human origin with epitope mapping at the C-terminus
  • recommended for detection of GRK 1 of mouse, rat, human, bovine and avian origin by WB, IP, IF and ELISA
  • available conjugated to agarose for IP
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GRK 1 Antibody (G-8) for WB applications. These reagents are now offered in bundles with GRK 1 Antibody (G-8) (see ordering information below).

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GRK 1 Antibody (G-8) is a mouse monoclonal IgG1 antibody that detects GRK 1 in mouse, rat, human, bovine, and avian species by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GRK 1, also known as rhodopsin kinase, plays a crucial role in the regulation of G protein-coupled receptors (GPCRs) by phosphorylating them in their activated state, which is essential for the process of agonist-mediated desensitization. This phosphorylation is vital as it prevents overstimulation of the receptor, thereby ensuring that cellular responses to external signals are appropriately modulated. The ability of GRK 1 to specifically target activated receptors helps maintain cellular homeostasis and prevents potential pathological conditions that could arise from excessive signaling. GRK 1 (G-8) monoclonal antibody is an invaluable tool for researchers studying GPCR signaling pathways and their implications in various physiological and pathological processes.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

GRK 1 Antibody (G-8)

sc-8004
200 µg/ml
$316.00

GRK 1 Antibody (G-8): m-IgG Fc BP-HRP Bundle

sc-536560
200 µg Ab; 10 µg BP
$354.00

GRK 1 Antibody (G-8): m-IgGκ BP-HRP Bundle

sc-533711
200 µg Ab; 40 µg BP
$354.00

GRK 1 Antibody (G-8): m-IgG1 BP-HRP Bundle

sc-544675
200 µg Ab; 20 µg BP
$354.00

GRK 1 Antibody (G-8) AC

sc-8004 AC
500 µg/ml, 25% agarose
$416.00

Are there any issues with using sc-8004: GRK 1 (G-8) mouse monoclonal primary antibody on mouse samples?

Asked by: Randy McDonald
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-8004 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 5 out of 5 by from GRK 1 (G-8) AntibodyThe Ab worked well on 4% PFA fixed sections of mouse retina
Date published: 2022-04-06
Rated 5 out of 5 by from Works great!We bought this antibody because our older, frozen stock wasn't working. This antibody worked well (good signal strength and specificity for ROS) for both frozen sections and fixed, whole mounted tissues from mouse.
Date published: 2021-09-08
Rated 5 out of 5 by from Band detected at expected mw in bovine retinaBand detected at expected mw in bovine retina rod outer segment suspension. -SCBT QC
Date published: 2015-06-08
Rated 5 out of 5 by from Good specificity and signal strength in bovineGood specificity and signal strength in bovine retina rod outer segment suspension. -SCBT QC
Date published: 2015-05-05
Rated 5 out of 5 by from Successful application of this antibody in WBSuccessful application of this antibody in WB, IHC and IF using human HepG2 -SCBT Publication Review
Date published: 2015-02-16
Rated 5 out of 5 by from This antibody was used in a publication forThis antibody was used in a publication for WB on mouse retina - SCBT Publication Review
Date published: 2015-02-09
Rated 5 out of 5 by from Publishable IF data with rat TGRPublishable IF data with rat TGR-1, TGR-1/MycER, Smoxi, and M47-Cells - SCBT Publication Review
Date published: 2014-09-16
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GRK 1 Antibody (G-8) is rated 5.0 out of 5 by 7.
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