GRK 1 Antibody (G-8) is a mouse monoclonal IgG1 antibody that detects GRK 1 in mouse, rat, human, bovine, and avian species by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GRK 1, also known as rhodopsin kinase, plays a crucial role in the regulation of G protein-coupled receptors (GPCRs) by phosphorylating them in their activated state, which is essential for the process of agonist-mediated desensitization. This phosphorylation is vital as it prevents overstimulation of the receptor, thereby ensuring that cellular responses to external signals are appropriately modulated. The ability of GRK 1 to specifically target activated receptors helps maintain cellular homeostasis and prevents potential pathological conditions that could arise from excessive signaling. GRK 1 (G-8) monoclonal antibody is an invaluable tool for researchers studying GPCR signaling pathways and their implications in various physiological and pathological processes.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GRK 1 Antibody (G-8) | sc-8004 | 200 µg/ml | $316.00 | |||
GRK 1 Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-536560 | 200 µg Ab; 10 µg BP | $354.00 | |||
GRK 1 Antibody (G-8): m-IgGκ BP-HRP Bundle | sc-533711 | 200 µg Ab; 40 µg BP | $354.00 | |||
GRK 1 Antibody (G-8): m-IgG1 BP-HRP Bundle | sc-544675 | 200 µg Ab; 20 µg BP | $354.00 | |||
GRK 1 Antibody (G-8) AC | sc-8004 AC | 500 µg/ml, 25% agarose | $416.00 |