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Glut4 Antibody (H-61): sc-7938

 |  Datasheet

(Based on data analysis)

  • Glut4 Antibody (H-61) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 230-290 mapping within an internal region of Glut4 of human origin
  • recommended for detection of Glut4 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • See 40 citations for Glut4 Antibody (H-61)
 
Full-length Glut4 protein sequence with immunogen highlighted:
MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVKPSTELEYLGPDEND

See additional Glut Antibodies including Glut, Glut1, Glut14, Glut2, Glut3, Glut4, Glut5, Glut6, Glut7, Glut8, Glut9, Glut10, Glut11 and Glut12.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Glut4 Antibody (H-61) sc-7938 200 µg/ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Glut4 CRISPR/Cas9 KO Plasmid (m) sc-423001 20 µg $345
Glut4 HDR Plasmid (m) sc-423001-HDR 20 µg $385
Glut4 CRISPR/Cas9 KO Plasmid (h) sc-400158 20 µg $345
Glut4 HDR Plasmid (h) sc-400158-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Glut4 siRNA (h) sc-41220 10 µM $258
Glut4 siRNA (m) sc-41221 10 µM $258
Glut4 siRNA (r) sc-270138 10 µM $258
Glut4 (h)-PR sc-41220-PR 10 µM, 20 µl $23
Glut4 (m)-PR sc-41221-PR 10 µM, 20 µl $23
Glut4 (r)-PR sc-270138-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Glut4 shRNA Plasmid (h) sc-41220-SH 20 µg $520
Glut4 shRNA Plasmid (m) sc-41221-SH 20 µg $520
Glut4 shRNA Plasmid (r) sc-270138-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Glut4 shRNA (h) Lentiviral Particles sc-41220-V 200 µl $625
Glut4 shRNA (m) Lentiviral Particles sc-41221-V 200 µl $625
Glut4 shRNA (r) Lentiviral Particles sc-270138-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
3T3-L1 Cell Lysate sc-2243 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SLC2A4 6517 17p13.1 NM_001042 P14672
138190
Mouse Slc2a4 20528 11 B3 P14142
N/A
 


Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter, Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve-pass transmembrane proteins (12TM) whose carboxy-termini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.

Glut4 Antibody (H-61) Product Citations
See how others have used Glut4 Antibody (H-61) and or Glut4 Antibody (H-61) conjugates.


40 total citations
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Glut4 Antibody (H-61) Data
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Glut4 (H-61): sc-7938. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.
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