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- goat polyclonal IgG, 200 µg/ml
- raised against a peptide mapping at the N-terminus of the mature chain of Collagen α1 Type II of human origin
- recommended for detection of Collagen α1 type II of mouse, rat, human and Xenopus origin by WB, IP, IF and ELISA
- blocking peptide, sc-7764 P
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COL2A1 Background Information
The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.
| COL2A1 (N-19) Product Citations |
See how others have used COL2A1 (N-19): sc-7764 antibody and or COL2A1 (N-19) antibody conjugates.
10 total citations Loading citations.
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COL2A1 (N-19)
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COL2A1 (N-19): sc-7764. Immunofluorescence staining of methanol-fixed ECV304 cells showing cytoplasmic localization.
COL2A1 (N-19): sc-7764. Western blot analysis of COL2A1 expression in HISM whole cell lysate.
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