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EAAT2 Antibody (N-19): sc-7760

 |  Datasheet

(Based on data analysis)

  • EAAT2 Antibody (N-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of EAAT2 of human origin
  • recommended for detection of EAAT2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including porcine
  • blocking peptide, sc-7760 P
  • See 11 citations for EAAT2 Antibody (N-19)
 

See additional EAAT Antibodies including EAAT, EAAT1, EAAT2, EAAT3, EAAT4 and EAAT5.

Also see EAAT2 Inhibitors for functional analysis of cellular responses to EAAT2.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
EAAT2 Antibody (N-19) sc-7760 200 µg/ml $279
EAAT2 (N-19) P sc-7760 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EAAT2 siRNA (h) sc-35255 10 µM $258
EAAT2 siRNA (m) sc-35256 10 µM $258
EAAT2 siRNA (r) sc-270106 10 µM $258
EAAT2 (h)-PR sc-35255-PR 10 µM, 20 µl $23
EAAT2 (m)-PR sc-35256-PR 10 µM, 20 µl $23
EAAT2 (r)-PR sc-270106-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EAAT2 shRNA Plasmid (h) sc-35255-SH 20 µg $520
EAAT2 shRNA Plasmid (m) sc-35256-SH 20 µg $520
EAAT2 shRNA Plasmid (r) sc-270106-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EAAT2 shRNA (h) Lentiviral Particles sc-35255-V 200 µl $625
EAAT2 shRNA (m) Lentiviral Particles sc-35256-V 200 µl $625
EAAT2 shRNA (r) Lentiviral Particles sc-270106-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
rat brain extract sc-2392 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SLC1A2 6506 11p13 NM_004171 P43004
600300
Mouse Slc1a2 20511 2 E2 P43006
N/A
 


Excitatory amino acid transporter 1 (EAAT1) is one of the two glial glutamate transporters that clear the extracellular glutamate generated during neuronal signal transmission. Excitatory amino acid transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The reuptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. Three glutamate transporters have been identified in human brain, designated EAAT1-3. EAAT1 and EAAT3 are also expressed in various non-nervous tissues, while EAAT2 expression appears to be restricted to the brain. Surface expression of the glial glutamate transporter EAAT1 is stimulated by insulin-like growth factor 1 through activation of phosphatidylinositol-3-kinase.

EAAT2 Antibody (N-19) Product Citations
See how others have used EAAT2 Antibody (N-19) and or EAAT2 Antibody (N-19) conjugates.


11 total citations
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EAAT2 Antibody (N-19) Data
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EAAT2 (N-19): sc-7760. Western blot analysis of EAAT2 expression in rat brain extract.
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