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NF-YC (N-19)-R Antibody: sc-7715-R |
| Datasheet |
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- rabbit polyclonal IgG, 200 µg/ml
- epitope mapping at the N-terminus of NF-YC of human origin
- recommended for detection of NF-YC of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-7715 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-7715 X, 200 µg/0.1 ml
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
NFYC |
4802 |
1p34.2 |
NM_014223 |
Q13952
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605344 |
| Mouse |
Nfyc |
18046 |
4 D2.2 |
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P70353
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N/A |
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NF-YC Background Information The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB, and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold “handshake” motif in a manner analogous to the histone proteins H2B and H2A, respectively. |
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NF-YC (N-19)-R
Click on image to enlarge
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NF-YC (N-19): sc-7715. Western blot analysis of NF-YC expression in K-562 (A), untreated HeLa (B), PMA-treated HeLa (C), Jurkat (D) and A-673 (E) nuclear extracts.
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