epitope mapping near the C-terminus ofNF-YB of human origin
recommended for detection of NF-YB of mouse, rat and human origin by WB, IF and ELISA; may cross-react with Syndecan 1 in mouse and rat; also reactive with additional species, including equine, canine, bovine, porcine and avian
blocking peptide, sc-7711 P
TransCruz reagent for Gel Supershift and ChIP applications, sc-7711 X, 200 µg/0.1 ml
NF-YB Background Information The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukar-yotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold “handshake” motif in a manner analogous to the histone proteins H2B and H2A, respectively.
NF-YB (C-20) Product Citations
See how others have used NF-YB (C-20): sc-7711 antibody and or NF-YB (C-20) antibody conjugates.
