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home » Signaling Intermediates » Pulmonary Surfactant-Associated Protein Antibody / Pulmonary Surfactant-Associated Protein Antibodies » SP-B (C-20)-R: sc-7702-R

SP-B (C-20)-R Antibody: sc-7702-R

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of SP-B of human origin
  • recommended for detection of SP-B of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and bovine
  • blocking peptide, sc-7702 P
 
Additional Pulmonary Surfactant-Associated Protein Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SFTPB 6439 2p11.2 NM_000542, NM_198843 P07988
 265120
Mouse Sftpb 20388 6 C1 P50405
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
SP-B (C-20) P sc-7702 P
(peptide)
 100 µg/0.5 ml $61
SP-B (C-20)-R sc-7702-R 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
SP-B siRNA (h) sc-36537 10 µM $258
SP-B siRNA (m) sc-36538 10 µM $258
SP-B (h)-PR sc-36537-PR 10 µM $23
SP-B (m)-PR sc-36538-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
SP-B shRNA Plasmid (h) sc-36537-SH 20 µg $520
SP-B shRNA Plasmid (m) sc-36538-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
SP-B shRNA (h) Lentiviral Particles sc-36537-V 200 µl $625
SP-B shRNA (m) Lentiviral Particles sc-36538-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
mouse lung extract sc-2390 500 µg/200 µl $104

SP-B Background Information
Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
 
SP-B (C-20)-R
Click on image to enlarge
sc-7702
SP-B (C-20): sc-7702. Western blot analysis of the glycosylated precursor form of SP-B expression in WI 38 whole cell lysate.
sc-7702-R
SP-B (C-20)-R: sc-7702-R. Western blot analysis of SP-B expression in A549 whole cell lysate (A) and mouse lung (B) and rat lung (C) tissue extracts.
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